IARC Monographs on the Identification of Carcinogenic Hazards to Humans

项目总结/摘要 自1971年以来，IARC关于识别对人类致癌危害的专著 提供了一个以证据为基础的方法，以确定人类疾病的可预防原因， 癌世界各地的组织都依赖IARC的专著作为一个值得信赖的来源， 致癌性评估在他们努力控制癌症。由 专著包括化学品、物理和生物制剂、复杂的混合物， 职业暴露环境和日常生活中的其他暴露。迄今为止，1021 121种被列为“致癌”，89种被列为“可能”， 致癌”，315对人类“可能致癌”。选择代理的目的是 根据人类接触和致癌性以及公共健康的证据进行评价 重要性各论由独立的全球专家编写，没有冲突， 兴趣各论包括相关科学文献的系统综述 涵盖了三个独特的证据流（人类癌症，实验性癌症）， 动物和机械证据）。的

Project Summary/Abstract Since 1971, the IARC Monographs on the Identification of Carcinogenic Hazards to Humans has provided an evidence-based approach to identifying the preventable causes of human cancer. Organizations worldwide rely on the IARC Monographs as a trustworthy source of carcinogenicity evaluations in their efforts to control cancer. Agents evaluated by the Monographs encompass chemicals, physical and biological agents, complex mixtures, occupational exposure circumstances, and other exposures of everyday life. To date, 1021 agents have been evaluated, with 121 classified as “carcinogenic”, 89 as “probably carcinogenic”, and 315 as “possibly carcinogenic” to humans. Agents are selected for evaluation based on evidence of human exposure and of carcinogenicity, and public health importance. Monographs are developed by independent global experts without conflicts of interest. Each Monograph includes systematic reviews of the pertinent scientific literature covering three unique streams of evidence (cancer in humans, cancer in experimental animals, and mechanistic evidence). The