System for Annulus Fibrosus Repair (SAFR) – a percutaneously implantable preformed biomaterial for the repair of defects caused by either degenerative disc disease or needle puncture during nucleus pulposus replacement procedures SAFR

SAFR旨在解决纤维环修复装置的现有市场挑战，以防止在任何微创椎间盘切除术或手术针头穿刺纤维环时发生髓核物质的挤压。OrthoSon的目标是将一种创新的、颠覆性的简单解决方案推向市场，该解决方案起源于英国，能够以比目前竞争对手技术更高的效率和更低的成本修复这些纤维环缺陷。OrthoSon是一家发展迅速、资金雄厚的公司，从牛津大学剥离出来，其使命是通过使用技术恢复退变的椎间盘来减轻背痛，这是全球最大的致残原因。SAFR是一种新产品，与OrthoSon的使命相辅相成，解决了另一个全球临床未满足的需求。由OrthoSon公司领导并负责该设备的整体开发和商业化，项目合作伙伴伦敦帝国理工学院将利用其专业的脊柱植入物测试设施，开发测试过程并评估结果；而East Midlands Spine是一家专业的脊柱治疗和咨询公司，将为设备设计提供临床投入。

The SAFR seeks to address the existing market challenge for an annulus fibrosus repair device to prevent the extrusion of nucleus pulposus material that occurs during any minimally invasive discectomy treatment or surgical needle puncture to the Annulus Fibrosus. OrthoSon aims to bring to market an innovative, disruptively simple solution of UK origin that enables the repair of these annulus fibrosus defects with a much greater efficacy rate than is currently available from competitor technology today and at a lower cost.OrthoSon is a rapidly developing, well-funded company, spun out of the University of Oxford with a mission to alleviate back pain, the largest cause of global disability, by using technology to restore the degenerated intervertebral disc. SAFR is a new product, complementary to OrthoSon's mission, that addresses another global clinical unmet need.With OrthoSon as lead and responsible for the overall development and commercialisation of the device, project partners Imperial College London, leveraging their specialist spinal implant testing facility, will develop the testing process and evaluate findings; while East Midlands Spine, a specialist spinal treatment and consultancy company, will provide clinical input on device design.