Columbia University Graduate Training Program in Microbiology and Immunology

这份重新提交的申请要求NIH重新支持这位哥伦比亚大学的博士前研究生 微生物学和免疫学培训计划。请求为各4个培训补助金职位提供支助 年，如上一个周期。我们的博士学位授予计划提供了一个独特的博士前学员 有机会在广泛而有凝聚力的科学探究计划中获得个性化的培训， 免疫系统，宿主对感染的反应，病原体生物学，微生物学的系统方法， 免疫学、癌症免疫学、人类免疫学、移植以及微生物和 免疫细胞复制它超越了传统的微生物学和免疫学的界限， 我们的研究兴趣集中在三个跨学科主题上：i）免疫细胞和组织发育， 稳态，包括对人类免疫学的主要强调; ii）病原体生物学和宿主反应;以及 iii）DNA复制和修复及其与细胞增殖的联系，包括影响细胞增殖的癌性过程。 免疫系统我们的23位导师，主要在基础科学或医学部门任职， 哥伦比亚大学欧文医学中心（CUIMC），展示了杰出的研究和培训记录。 大多数导师被任命为微生物学和免疫学系，该系负责管理这一项目。 程序.受训人员学习微生物学和免疫学、分子遗传学、生物化学、细胞 生物学、计算和定量生物学以及负责任的研究行为。学生也报名参加 关于科学写作、资助准备和评论的研讨会。学员还必须通过资格考试， 测试他们制定和捍卫假设驱动项目的能力的考试。我们的研究生课程 由我们的主任大卫菲多克博士和副主任乌蒂亚巴苏博士领导。我们的计划框架 包括一个咨询委员会，定期评估学生和培训师的表现，课程， 培训补助金合格申请人;初级培训员辅导计划;外部审查委员会 由三名计划总监组成，他们定期提供反馈，以帮助优化计划的有效性。在 自从我们的研究生项目首次获得NIAID资助以来的六年里，我们一直在招募 优秀的学生群体，平均GPA为3.6，平均21个月的全职收入 我们的TGE参赛者的研究经验，谁构成了我们的参赛者的90%。代表性不足的少数群体， 我们积极寻求招募的人，占我们同龄人的17%。我们的计划正在蓬勃发展，这一点可以从 过去和现在的受训人员的杰出出版记录。超过95%的毕业生留在了 科学或与科学相关的领域。我们还受益于我们的院长和办公室的强有力的机构支持 研究生事务，以及在CUIMC许多科学，教育和职业发展资源。 我们充满活力，严谨和丰富的研究生课程致力于培养未来的领导者和创新者 微生物学和免疫学研究。

This resubmitted application requests renewed NIH support for the predoctoral Columbia University Graduate Training Program in Microbiology and Immunology. Support is requested for four training grant positions each year, as per the previous cycle. Our PhD granting program provides predoctoral trainees with a unique opportunity to obtain individualized training within a broad yet cohesive program of scientific inquiry into the immune system, host response to infection, pathogen biology, systems approaches to microbiology and immunology, cancer immunology, human immunology, transplantation, and processes of microbial and immune cell replication. Extending beyond traditional boundaries that separate microbiology and immunology, our research interests converge on three cross-disciplinary themes: i) immune cell and tissue development and homeostasis, including a major emphasis on human immunology; ii) pathogen biology and host response; and iii) DNA replication and repair and their links to cell proliferation, including cancerous processes affecting the immune system. Our 23 preceptors, with primary appointments in basic science or medical departments at the Columbia University Irving Medical Center (CUIMC), demonstrate outstanding research and training records. Most preceptors are appointed to the Department of Microbiology and Immunology, which administers this program. Trainees take courses in microbiology and immunology, molecular genetics, biochemistry, cell biology, computational and quantitative biology, and responsible conduct in research. Students also enroll in workshops on scientific writing, grant preparation, and critiquing. Trainees must also pass a qualifying examination that tests their ability to formulate and defend a hypothesis-driven project. Our graduate program is led by our Director Dr. David Fidock and Associate Director Dr. Uttiya Basu. Our programmatic framework includes an Advisory Committee that regularly evaluates student and trainer performance, the curriculum, and Training Grant Eligible applicants; a mentoring plan for junior trainers; and an External Review Board comprised of three Program Directors who provide regular feedback to help optimize program effectiveness. In the six years since our Graduate Program was first awarded NIAID funding, we have consistently recruited an excellent cohort of students, with a mean GPA of 3.6 and an average of 21 months of full-time incoming research experience for our TGE entrants, who constituted 90% of our entrants. Underrepresented minorities, who we actively seek to recruit, comprised 17% of our cohort. Our program is flourishing, as evidenced by the exceptional publication record of past and current trainees. Over >95% of our graduates have remained in science or science-related fields. We also benefit from strong institutional support from our Dean and the Office of Graduate Affairs, as well as the many scientific, educational and career development resources at CUIMC. Our dynamic, rigorous and enriching graduate program is committed to training future leaders and innovators in microbiology and immunology research.