Delaware INBRE

项目摘要-生物信息学核心 生物信息学现在在支持生物医学和所有生命科学的研究方面发挥着核心作用；数据密集型 像RNA测序这样的研究方法已经成为基础技术。今天的研究人员必须 掌握这些技术如何推进其研究的概念。支持不断增长的 多样化的信息学需求，生物信息学核心必须演变为不仅提供计算基础设施和 执行高通量数据分析的专业知识，但也越来越多地充当教育驱动中心 培训精通信息的研究人员，他们可以有效地利用和解释数据。已经建立起强大的 在以前的DE-INBRE资助周期下，特拉华州的生物信息学资源基金会，生物信息学 CORE将进一步扩大其在全州的影响和影响。 DE-INBRE生物信息学核心组织为特拉华州生物信息学网络(BIND)，具有方向盘 一个委员会，包括来自所有合作机构的代表，帮助指导和塑造特拉华州INBRE 生物信息学倡议并创造协同效应，以满足该计划不断发展的需求。特别是，DE-INBRE IV 将增加目前集中在特拉华大学的生物信息学资源和专业知识的可及性 特拉华州立大学(DSU)生物成像和计算神经科学，以及生物医学和临床 Nemour/Alfred I.DuPont儿童医院(Nemour)和克里斯蒂安娜关怀中心的信息学资源 在DE-INBRE伙伴机构中建立卫生系统(CCHS)，以提供信息学网络基础设施， 促进生机勃勃的生物医学研究所需的研究支持、教育计划和研究暴露 特拉华州的载客量。 具体目标 1.支持DE-INBRE扩大的生物医学研究网络。 2.提升特拉华州的生物医学研究能力。 3.支持特拉华州的生物医学研究倡议。 4.提高特拉华州劳动力的科学技术知识。

Project Summary – Bioinformatics Core Bioinformatics now plays a central role in supporting research in biomedical and all life sciences; data-intensive research methodologies like RNA sequencing have become foundational techniques. The researchers of today must have a grasp of the concepts for how these technologies can advance their research. To support the growing and diversified informatics needs, bioinformatics cores have to evolve to not only provide computational infrastructure and the expertise to perform high-throughput data analysis, but also increasingly to serve as centers of education driving the training of informatically savvy researchers who can effectively utilize and interpret the data. Having built strong foundations for bioinformatics resources in Delaware under previous DE-INBRE funding cycles, the Bioinformatics Core will further expand its reach and impact throughout the State. The DE-INBRE Bioinformatics Core is organized as a Bioinformatics Network of Delaware (BiND) with a Steering Committee that includes representatives from all Partner Institutions to help guide and shape Delaware INBRE’s bioinformatics initiatives and create synergies to meet the evolving needs of the program. In particular, DE-INBRE IV will increase accessibility of bioinformatics resources and expertise currently concentrated at University of Delaware (UD), bio-imaging and computational neuroscience at Delaware State University (DSU), and biomedical and clinical informatics resources housed at Nemours/Alfred I. duPont Hospital for Children (Nemours) and Christiana Care Health System (CCHS) among the DE-INBRE Partner Institutions to provide the informatics cyberinfrastructure, research support, educational programs, and research exposures needed to promote a vibrant biomedical research capacity in the State of Delaware. Specific Aims 1. Support DE-INBRE’s expanded Biomedical Research Network. 2. Enhance Delaware’s biomedical research capacity. 3. Support biomedical research initiatives in Delaware. 4. Enhance the science and technology knowledge of Delaware’s workforce.