Ga. Dept. of Agriculture - NARMS

NARMS -项目概要/摘要 格鲁吉亚农业部（GDA）是负责监管农业的国家机构。 食品生产设施和零售机构。GDA实验室（实验室）是主要服务 实验室的监管计划，并专注于食品分析的化学和 微生物污染物。自2011年以来，GDA一直在寻求FDA的赠款和合作协议， 提高和协调我们国家的监管和测试能力。通过这些赠款，实验室 获得ISO 17025国际标准认证，使我们的监管机构能够 代表林业发展局履行合同工作。由于GDA是格鲁吉亚食品零售的监管机构 该机构在整个格鲁吉亚州都有检查员。这些 检查员接受过收集样本并将其送回我们实验室进行测试的培训， 监管执法。 由于GDA已经有了专门用于在零售场所进行样本采集的基础设施， 和微生物的分析实验室，这个奖项的机会NARMS（国家抗菌药物 阻力分类系统）应该很好地适合GDA实施。格鲁吉亚号 公共卫生部（GDPH）实验室目前获得了这笔赠款，但已联系GDA 由于COVID 19大流行已成为他们的首要任务，因此他们无法请求援助或接管。 总之，GDA检查员将按照常规采集样本并将其发送到实验室 协议.实验室会筛选样本，以找出拨款建议的目标生物 机会奖（FOA）。实验室将利用项目方案中描述的方法， 通过经批准和验证的ELISA或PCR平台进行筛选。显示典型特征的分离株将 进一步检查和确认或送交FDA作进一步评估。根据需要，GDPH已同意 也协助在全基因组测序的分离，因为GDA目前没有， 能力，除了指导的方法和程序，直到完全建立。 实验室已与其监管合作伙伴建立并展示了成功的关系 以及GDPH实验室，该实验室应表明其实现这一目标的能力。实验室还定期 每年对零售食物样本进行数以千计的微生物分析。如果被授予，GDA将 能够提高和加强抗菌素耐药性监测数据。这反过来可以是 用于向公共卫生利益相关者通报耐药菌株的种群情况，以及当前的政策和 这些做法足以保障消费者的整体安全。

NARMS - Project Summary/Abstract The Georgia Department of Agriculture (GDA) is the state agency responsible for regulation of food manufactured facilities and retail establishments. GDA Laboratories (Lab) are the primary servicing laboratories for the regulatory programs and are focused on food analysis for chemical and microbiological contaminants. Since 2011, GDA has pursued FDA grants and cooperative agreements to improve and harmonize our state regulatory and testing capability. Through these grants the Lab achieved accreditation to ISO 17025 international standards which allows our regulatory agencies to perform contractual work on behalf of FDA. Since GDA is Georgia’s regulatory authority over food retail establishments, the agency has inspectors positioned all throughout The State of Georgia. These inspectors are trained to collect samples and return them to our lab for testing that can support regulatory enforcement. Since GDA already has infrastructure designated for sample collection at retail establishments and the analysis of microorganisms by the Lab, this award opportunity NARMS (National Antimicrobial Resistance Monitory System) should make a good fit to be implemented by GDA. The Georgia Department of Public Health (GDPH) Laboratory is currently awarded this grant but has contacted GDA to request assistance or taking it over since the COVID 19 pandemic has become their top priority. In summary, GDA inspectors will collect the samples and send them to the Lab per routine protocols. The Lab will screen the samples for the target organisms suggested in the Funding Opportunity Award (FOA). The Lab will utilize methods described in the project protocol in addition to screening by approved and validated ELISA or PCR platforms. Isolates showing typical characteristics will be further examined and confirmed or sent to FDA for further evaluation. As needed, GDPH has agreed to also assist in in Whole Genome Sequencing of the isolates, since GDA does not currently have that ability, in addition to mentoring of the methods and program until fully established. The Lab has developed and demonstrated successful relationships with their regulatory partners and the GDPH Lab, which should indicate its ability to fulfill this objective. The Lab also routinely performs thousands of microbiological analyses on retail food samples annually. If awarded, GDA will be capable of enhancing and strengthening antimicrobial resistance surveillance data. This in turn can be used to inform public health stakeholders about populations of resistant strains and if current policy and practices are adequate for overall safety of consumers.