Neurochemical & Behavioral Correlates of ETOH Effects

项目摘要 该提案是为竞争继续T32培训计划的神经化学和行为 德克萨斯大学奥斯汀分校5名博士前研究员和3名博士后研究员的乙醇效应相关性。这 一个多学科的计划有着悠久的历史，培养博士前和博士后研究员在创新 与酒精滥用有关的研究问题，以帮助国家努力培养下一代 独立科学家专注于酒精相关研究。与国际知名的 瓦格纳酒精和成瘾研究中心，我们的培训环境和机会是特殊的， 由来自七个研究单位的14名教师组成的多元化和高度协作的小组提供 （行为神经科学，临床心理学，分子生物科学，神经病学，神经科学， 药理学-毒理学和精神病学）和四个研究生课程（细胞和分子生物学， 神经科学、药理学-毒理学和心理学）。主要目标是提供严格的， 艺术研究培训包括细胞和动物模型以及人类受试者的研究， 创新方法的广度，包括分子生物学和遗传学，生物信息学，细胞成像， 电生理学、神经解剖学、神经化学、人体成像和行为。学员们沉浸在 酒精研究领域由瓦格纳提供的知识环境的动态文化促进 中心和神经科学研究所。其他目标包括培训有效的科学 沟通以及专业和职业发展。方案内容加强了 经验，包括关于严格性和再现性，负责任的行为， 研究，资助写作，科学交流和酒精杂志俱乐部。多个呈现 学员的机会，可在一些研讨会系列，当地座谈会，和T32的新作品- 进行中的会议。博士预科学生将被要求完成一系列的核心课程要求， 在培训教师的直接指导下完成研究里程碑，并满足部门要求 最终获得博士学位。℃下博士后培训将为期三年，包括重点酒精 由教师导师指导的研究，并与专业发展活动相结合， 培训计划。我们将继续专注于从多元化和代表性不足的群体中招募学员 并支持UT在多样性，准入，公平和包容性方面的举措，以实现教师的多元化，这将 帮助我们的招聘工作。卓越的设施，资源和所有培训的承诺 水平提供了一个优秀的研究培训环境，为我们的学员在研究中取得成功做好准备- 密集的职业生涯集中在滥用酒精的原因和后果。

PROJECT SUMMARY This proposal is for the competing continuation of a T32 training program on the Neurochemical & Behavioral Correlates of EtOH Effects for 5 predoctoral and 3 postdoctoral fellows at The University of Texas at Austin. This multidisciplinary program has a long history of training predoctoral and postdoctoral fellows in innovative research questions related to alcohol misuse to help the national effort of producing the next generation of independent scientists focused on alcohol-related research. Intertwined with the internationally renowned Waggoner Center for Alcohol & Addiction Research, our training environment and opportunities are exceptional, provided by a diverse and highly collaborative group of 14 faculty members from seven research units (Behavioral Neuroscience, Clinical Psychology, Molecular Biosciences, Neurology, Neuroscience, Pharmacology-Toxicology, and Psychiatry) and four graduate programs (Cellular and Molecular Biology, Neuroscience, Pharmacology-Toxicology, and Psychology). The primary objective to provide rigorous, state of the art research training includes research in cellular and animal models as well as human subjects and in a breadth of innovative approaches including molecular biology and genetics, bioinformatics, cellular imaging, electrophysiology, neuroanatomy, neurochemistry, human imaging and behavior. Trainees are immersed in the alcohol research field facilitated by the dynamic culture of the intellectual environment provided by the Waggoner Center and the Institute for Neuroscience. Additional objectives include training in effective scientific communication as well as professional and career development. Programmatic elements enhance the experience, including required courses and seminars on Rigor and Reproducibility, Responsible Conduct of Research, Grant Writing, Scientific Communication, and Alcohol Journal Club. Multiple presentation opportunities for trainees are available in a number of seminar series, local symposia, and the T32’s new works- in-progress sessions. Predoctoral students will be required to complete a series of core course requirements, achieve research milestones under direct guidance of training faculty, and satisfy departmental requirements culminating in a Ph.D. degree. Postdoctoral training will be for three years and consist of focused alcohol research guided by a faculty mentor and coupled with professional development activities supported by the training program. We will continue to focus on recruiting trainees from diverse and under-represented groups and support UT’s initiatives in diversity, access, equity, and inclusion to diversify the faculty, which will subsequently aid in our recruiting efforts. Exceptional facilities, resources and commitment to training from all levels provide an outstanding research training environment to prepare our trainees for success in research- intensive careers focused on the causes and consequences of alcohol misuse.