Enhancing Exercise Intensity, Motivation and Enjoyment for Persons with PD: Comparing Visual Feedback and Competition in A Virtual Cycling Environment (VCYCLE)

项目摘要 在这项对33名帕金森病患者（PD，Hoehn和Yahr II-III期）的单组研究中， 在两个虚拟现实增强自行车条件下进行锻炼：视觉反馈和竞争。主 这项研究的目的是确定骑自行车的条件（视觉反馈或竞争）促进 在神经肌肉骨骼领域的运动强度更高（以每分钟转数测量）， 自行车）和心血管领域（通过最大值的%测量）。心率）以及促进更高 动机和享受（用内在动机量表测量）和减少对努力的感知 （用博格量表测量）。第二个目的是探讨个人因素（竞争力） 影响运动强度，以及视觉注意是否能区分骑车条件。 数据将在一个单一的会议，包括临床评估和骑自行车10分钟，为每个 在佩戴头戴式显示器以与虚拟环境交互的同时， 这项研究的结果将为最佳锻炼计划的设计提供信息， 对PD患者来说是一种享受。这些计划将被测试在改善流动性和健身的有效性 为PD患者带来福祉。 拟议的项目将在赞助商的指导下在设备齐全的实验室中进行 在为患有神经系统疾病的人设计虚拟现实工具方面有着悠久的历史。的 赞助商已经成功地指导了数十名研究生，包括双学位学生， 临床科学家来自不同培训背景和专业领域的合作者和贡献者将 与申办者和PI合作完成该项目。PI将把他以前的工程培训与新的 在应用科学中发展的技能。PI的培训计划包括与研究执行相关的目标， 传播、临床经验、教学/指导和社区/专业服务，所有这些都可以 现实地实现。

Project Summary In this single group study of 33 persons with Parkinson's Disease (PD, Hoehn and Yahr Stages II-III) will exercise in two virtual reality augmented bicycling conditions: visual feedback and competition. The primary purpose of the study is to determine which condition of bicycling (visual feedback or competitive) promotes a higher exercise intensity in the neuromusculoskeletal domain (measured by revolutions per minutes on the bicycle) and in the cardiovascular domain (measure by % of max. heart rate) as well as which promotes higher motivation and enjoyment (measured with the Intrinsic Motivation Inventory) and reduced perception of effort (measured with the Borg Scale). The secondary aims are to explore how personal factors (competitiveness) influence the exercise intensity, and whether visual attention can differentiate between the cycling conditions. Data will be collected in a single session consisting of clinical assessments and bicycling for ten minutes for each condition while wearing a head mounted display to interact with the virtual environment. Results from this study will inform the design of optimal exercise programs to make exercise accessible, enjoyable for persons with PD. Those programs will be tested for efficacy at improving mobility and fitness leading to well-being for persons with PD. The proposed project will be undertaken in a well-equipped laboratory under the mentorship of a sponsor with a long track record of designing virtual reality tools for persons with neurologic health conditions. The sponsor has successfully mentored dozens of graduate students including dual-degree students, training to be clinician scientists. Collaborators and contributors from diverse training backgrounds and areas of expertise will work with the sponsor and PI on this project. The PI will couple his previous training in engineering with new skills developed in applied science. The PI's training plan includes goals related to research execution and dissemination, clinical experience, teaching/mentoring, and community/professional service all of which can be realistically achieved.