RACE: RNA and Cell Biology - from Fundamental Research to Therapies

波兰的科学，包括生物医学研究，在过去的30年里取得了巨大的进步。然而，它在医学或商业应用方面的基础科学发现的进步仍然落后于全球顶尖国家。这种差距源于波兰研究人员在转化研究领域的有限经验。华沙国际分子和细胞生物学研究所（IIMCB）的目标是通过建设将基础知识转化为临床创新的能力和在波兰的科学环境中引入创业文化来缩小这一差距。自成立以来，IIMCB一直是波兰卓越研究和管理的灯塔。波兰政府认识到该研究所的成就和未来潜力，拨款建造一个扩建的现代化IIMCB总部，这将使我们的能力增加到20个研究小组。团队计划下的RACE项目将帮助我们实现这一现实，并成功将IIMCB升级为世界级的RNA和细胞生物学卓越转化研究中心。我们与我们的高级合作伙伴、医学研究理事会、爱丁堡大学人类遗传学单位（UoE-MRC HGU）和比利时VIB一起，确定了实现我们目标的五个具体目标，即：招募和培训下一代企业集团领导人和研究人员（目标1,2），建立适合商业用途的现代化和自我维持的核心设施（目标3），实施系统的技术转让（目标4）和行政支持（目标5）。最终，RACE项目将使IIMCB成为全国转化研究的参考模型，并将该研究所提升为欧洲研究中心的顶级研究中心，准备在科学前沿参与竞争性的欧盟和全球生物医学研究和创新项目。

Polish science, including biomedical research, has made huge advancesin the last 30 years. However, the advancement of itsfundamental scientific discoveries toward medical or commercial applications still lags behind the top countries, worldwide. This gap stems from the limited experience of Polish researchers in the field of translational research. The International Institute of Molecular and Cell Biology in Warsaw (IIMCB) aims to close this gap by building the capacity to translate basic knowledge into clinical innovations and by introducing an entrepreneurship culture in the scientific environment in Poland. Since its creation, the IIMCB has been a lighthouse of research and management excellence in Poland. Recognising the Institute’s achievements and future potential, the Polish government awarded funding to build an expanded, modern IIMCB headquarters, which will increase our capacity up to 20 research groups. The RACE project under the Teaming programme will help us achieve this reality and successfully upgrade the IIMCB to a world-class translational research Centre of Excellence in RNA and Cell Biology. Together with our Advanced Partners, the Medical Research Council, Human Genetics Unit of the University of Edinburgh (UoE–MRC HGU), and VIB in Belgium, we have identified five Specific Objectives that are key to achieve our goal, namely: recruitment and training of the next generation of entrepreneurial group leaders and researchers (Objectives 1, 2), establishment of modern and self-sustaining Core Facilities adapted to commercial use (Objective 3), implementation of systemic Technology Transfer (Objectives 4) and administrative support (Objective 5). Ultimately, the RACE project will make the IIMCB a reference model in translational research countrywide and elevate the Institute to the top tier of European research centres ready to engage in competitive EU and global biomedical research and innovation projects at the frontiers of science.