Yale Head and Neck Cancer SPORE Developmental Research Program

项目总结 头颈部癌耶鲁大学孢子开发研究计划的主要目标 (yhn-sporate)是确定和资助具有翻译潜力的创新试点项目 头颈癌领域在风险评估、早期发现、生物标记物等领域的影响 预后和治疗预测，致癌/肿瘤发生机制，新的治疗靶点， 开发新的治疗方法和新的治疗方法。资助发展项目的调查人员 强烈鼓励研究项目与研究机构内外的其他研究人员合作。 Yhn-孢子机构，包括其他孢子群落。其目的是为每个受资助的DRP 有可能演变成独立的全孢子项目或同等规模的研究建议的项目。 最终，与主要的yhn-sporate项目一起，这个项目的成果将有助于 降低美国和世界各地头颈部癌症的发病率和死亡率。DRP计划奖 委员会将成立，并将招募、评估和选择试点项目的创新建议，包括 头颈部癌的转译潜力。每年最多三个项目将在科学和财务上 得到yhn孢子的支持，并定期进行进展评估。

PROJECT SUMMARY The primary goal of the Developmental Research Program (DRP) of the Yale SPORE in Head & Neck Cancer (YHN-SPORE) is to identify and fund innovative pilot projects that possess translational potential to make an impact in the field of head & neck cancer in the areas of risk assessment, early detection, biomarkers for prognosis and therapy prediction, mechanisms of carcinogenesis/tumorigenesis, novel therapeutic targets, development of novel therapeutics, and novel treatment approaches. Investigators of funded developmental research projects are strongly encouraged to collaborate with other investigators within and outside of the YHN-SPORE institutions, including other SPORE communities. The purpose is to provide each funded DRP project with the potential to evolve into independent full SPORE projects or equivalent-scale study proposals. Ultimately, along with the main YHN-SPORE projects, the outcome from this program will contribute to the reduction of head & neck cancer morbidity and mortality in the US and worldwide. A DRP Program Award Committee will be formed and will recruit, evaluate, and select innovative proposals for pilot projects with translational potential for head & neck cancer. Up to three projects per year will be scientifically and financially supported by the YHN-SPORE, with regular progress evaluation.