IBEX bone health screening on mammography systems

该项目将展示一种独特的骨质疏松症筛查方法，使用广泛可用的乳房x光检查服务和筛查程序。骨质疏松症是一种影响超过20%的50岁以上女性的疾病。这种情况导致的脆弱性骨折对健康、死亡率和生活质量造成了毁灭性的影响，每年给全球医疗保健系统造成的损失超过4000亿美元。脆性骨折后：* 40%的患者无法独立行走* 60%的患者在至少一项基本的日常活动（如洗澡）中遇到困难* 80%的患者在其他活动（如开车或购物）中受到限制* 27%的患者第一次进入养老院尽管在骨质疏松症诊断后有有效的药物治疗来降低骨折风险，但没有常规的骨质疏松症筛查计划。目前该病有80%未被确诊，女性在确诊前通常会出现多处骨折。IBEX骨骼健康（IBEX BH）软件产品的开发是为了从常规x光片中识别骨骼健康状况，这些x光片是在其他调查中拍摄的，例如在骨折后。该项目将展示BH产品的可行性，该产品可以扩展到使用现有乳房x光检查设备和服务收集的简单手腕x光片，以及用于乳腺癌筛查和治疗的乳房x光照片，从而提供骨骼健康测量。乳房x光检查提供了一个独特的机会来识别骨骼健康状况不佳，因为有骨质疏松症风险的妇女是患骨质疏松症的高危人群。配合常规的乳房检查预约，通过在医院预约期间进行额外的手腕x光检查，为识别这一高危人群的骨质疏松症提供了一个绝佳的机会。长期目标是让所有女性在常规乳房x光检查的同时测量骨密度，并接受治疗，以避免使人衰弱的骨折，过上健康、积极的生活。

This project will demonstrate a unique method of screening for osteoporosis using widely available mammography services and screening programs.Osteoporosis is a condition that affects over 20% of women over the age of 50\. Fragility fractures resulting from the condition have a devastating impact on health, mortality and quality of life and cost the global healthcare system over $400bn per year. Following a fragility fracture:* 40% of patients are unable to walk independently* 60% encounter difficulties with at least one essential daily activity such as bathing* 80% are restricted in other activities such as driving or shopping* 27% enter a nursing home for the first timeDespite effective drug treatments being available to reduce risk of fractures following an osteoporosis diagnosis, there is no routine osteoporosis screening program. The condition is currently 80% underdiagnosed and women will typically suffer multiple fractures prior to a diagnosis.The IBEX Bone Health (IBEX BH) software product has been developed to opportunistically identify bone health from routine X-rays that have been taken for other investigations, for example following a fracture.This project will demonstrate the feasibility that the BH product can be extended to deliver a bone health measure from a simple wrist X-ray collected using existing mammography equipment and services alongside mammograms collected for breast cancer screening and treatment.Mammography provides a unique opportunity to identify poor bone health, since women at risk of osteoporosis are in the most at-risk demographic for developing osteoporosis. Aligning with their routine breast screening appointments offers a perfect opportunity to identify osteoporosis in this at-risk group by taking an additional wrist X-ray during their hospital appointment.The long-term vision is that all women have their bone density measured alongside their routine mammogram and are given the treatment to avoid debilitating fractures and live healthy, active lives.