Harnessing Data Science to Promote Equity in Injury and Surgery for Africa

项目摘要/摘要 创伤和其他手术治疗的情况是一种严重的、未解决的疾病负担， 在全球范围内对撒哈拉以南非洲(SSA)的影响不成比例。数据科学研究中心 非洲手术、伤害和公平(D-SINE-Africa)是布埃亚大学之间的战略合作伙伴关系 (BUEA)、加州大学(洛杉矶分校和伯克利分校)、喀麦隆公共事务部 卫生、喀麦隆非洲数学科学研究所和南部开普敦大学 非洲。D-Sine非洲将解决健康差距与风险因素和结果的交集问题 与SSA中的损伤和外科疾病相关。尽管数据比以往任何时候都更加丰富，但数据仍然有限 低收入和中等收入国家的资源。我们的方法将SSA中提供的“大数据”视为 有机会制定适用于资源受限环境的可持续的数据受限方法。 因此，将利用数据科学来解决我们中心的两个主要目标：1)减少 通过改进监测、预防和治疗来减轻伤害和外科疾病的负担；以及2) 改善喀麦隆和其他SSA国家获得高质量外科护理的机会。这些目标将会实现 通过三个具体目标：1)研究；2)建立网络；3)能力建设。这些目标得以实现 通过三个核心(管理、数据管理和分析以及能力建设核心)和两个 将在喀麦隆、南非和乌干达开展的研究项目。研究项目1--健康 股权监督解决了跟踪所需的快速社会经济(SES)评估方面的紧迫差距 通过将聚类算法应用于现有的公共可用资源来实现急诊护理环境中的健康公平 SSA的人口统计和健康调查数据集。研究项目2--创伤随访预测目标 通过使用机器学习优化基于手机的筛查调查来改善创伤结局 这将确定哪些创伤患者出院后将从进一步护理中受益 医院，根据中心的承诺，再次使用数据减少的方法，即从大数据到小数据 可持续的数据使用做法。这些项目利用共同数据来源(喀麦隆创伤登记处)， 具有协调一致的主题(伤害、公平和数据减少)，并将产生可一起使用的结果 (例如，确定易受后续护理不良影响的社会经济团体)。该中心创新性地构建了社区 将参与工具纳入内部咨询委员会，以促进建立信任的多方面办法 与研究参与者和最终用户合作。D-Sine非洲的努力将推动数据创新和影响 科学、伤害和公平研究，以改善获得外科疾病预防和护理的机会，包括 其SES合谋增加他们对受伤和手术条件的易感性，同时降低 外科护理通道。非洲的战略伙伴联合基础设施可供其 成员和整个DSI-非洲财团。

PROJECT SUMMARY/ABSTRACT Trauma and other surgically treated conditions are a crippling, unaddressed burden of disease that disproportionately impacts sub-Saharan Africa (SSA) globally. The Data Science Center for the Study of Surgery, Injury, and Equity in Africa (D-SINE-Africa) is a strategic partnership between the University of Buea (Buea), the University of California (Los Angeles (UCLA) and Berkeley), the Cameroonian Ministry of Public Health, the African Institute for Mathematical Sciences in Cameroon, and the University of Cape Town in South Africa. D-SINE Africa will address the intersection of health disparities with the risk factors and outcomes associated with injury and surgical disease in SSA. Although more abundant than ever, data is still a limited resource in low- and middle-income countries. Our approach views “big data” available in SSA as an opportunity to develop sustainable data-constrained approaches appropriate for resource-constrained settings. Thus, data science will be harnessed to address our Hub's two main goals which are;1) to decrease the burden of injuries and surgical diseases through improved surveillance, prevention, and treatment; and 2) to improve access to quality surgical care in Cameroon and other SSA countries. These goals will be achieved through three specific aims: 1) Research 2) Networking and 3) Capacity Building. These aims implemented through three cores (Administrative, Data Management and Analysis, and Capacity Building Cores) and two Research Projects that will be conducted in Cameroon, South Africa, and Uganda. Research Project 1 - Health Equity Surveillance addresses the urgent gap in rapid socioeconomic (SES) estimation necessary to track health equity in acute care settings by applying a clustering algorithm to existing publicly available Demographic and Health Surveys data sets for SSA. Research Project 2 – Trauma Follow Up Prediction aims to improve trauma outcomes by using machine learning to optimize a mobile phone-based screening survey that will identify which trauma patients would benefit from further care after they are discharged from the hospital, again using a data reduction “big data to small data” approach in line with the Hub's commitment to sustainable data use practices. These projects utilize common data sources (Cameroon Trauma Registry), have harmonizing themes (injury, equity, and data reduction), and will yield findings that can be used together (e.g., identification of SES groups vulnerable to poor follow up care). The Hub has innovatively built community engagement vehicles into the Internal Advisory Board to promote a multi-faceted approach to building trust with research participants and end-users. D-SINE Africa efforts will drive innovation and impact in data science, injury, and equity research to improve access to surgical disease prevention and care, including those whose SES conspires to increase their vulnerability to injury and surgical conditions while reducing consistent surgical care access. D-SINE Africa's strategic partners joint infrastructure are available for use by its members and DSI-Africa consortium at large.