Prediction, Monitoring and Personalized Recommendations for Prevention and Relief of Dementia and Frailty

COMFORTAGE是医学专家（即神经学家、精神病学家、神经心理学家、护士、记忆诊所）、社会科学家和人文学家、技术专家（即数据科学家、人工智能专家、机器人专家）和数字创新中心的共同努力，旨在建立一个泛欧洲框架，为与年龄相关的疾病和残疾提供基于社区、综合和以人为本的预防、监测和进展管理解决方案。该项目的框架将通过以下方面的独特组合和整合得到加强：(i)医疗/临床创新（例如，风险因素分析和个性化预测的新方法、基于人工智能的医疗设备、与年龄相关的临床证据的综合数据源和基于证据的医疗技术评估（HTA））； （ii）用于可信、准确、安全和个性化临床决策的尖端人工智能创新（例如，可解释的人工智能（XAI）、安全人工智能、严肃游戏、患者数字双胞胎、虚拟辅助技术）；（三）数字创新中心（如智能家居、机器人和生活实验室），以促进和促进健康和福祉领域的研究活动；（四）社会创新，促进创新观点，共同创造新的或改进的解决方案，以帮助和改善社会融合和互动。COMFORTAGE将促进大量不同数据源的整合、协调和管理，包括生物库、队列、医疗记录、纵向观察研究、关于患者的真实数据，以及可替代的次要数据源，如传感器、可穿戴设备和移动设备，在一个称为整体健康记录（hhr）的标准化结构中。COMFORTAGE将成为一种催化剂，帮助预防、监测和管理与年龄有关的疾病和残疾的进展，特别是痴呆症和虚弱，其基础是对上述技术的利用进行高端研究和分析

COMFORTAGE is a joint effort of medical experts (i.e., neurologists, psychiatrists, neuropsychologists, nurses, memory clinics), social scientists and humanists, technical experts (i.e., data scientists, AI experts, robotic experts) and Digital Innovation Hubs to establish a pan European framework for Community-based, Integrated and People-Centric prevention, monitoring and progression managing solutions for age-related diseases and disabilities. The project’s framework will be empowered by a unique combination and integration of: (i) Medical/clinical innovations (e.g., novel approaches to risk factor analysis and personalized prediction, AI-based medical devices, integrated data sources of age-related clinical evidence, and evidence-based Healthcare Technology Assessment (HTA)), (ii) Cutting edge AI innovations (e.g., explainable AI (XAI), secure AI, serious games, Patient Digital Twins, Virtual Assistive technologies) for trusted, accurate, secure and personalized clinical decision making, (iii) Digital Innovation Hubs (e.g. Smart Homes, robotics and Living Labs) to facilitate and promote research activities in the health and wellbeing domain, and (iv) social innovations for promoting innovative views and co-creating new or improved solutions for assistance and improvement of social integration and interaction. COMFORTAGE will facilitate the integration, harmonization, and management of a host of different data sources, including biobanks, cohorts, medical records, longitudinal observational studies, real-world data about patients, as well of alternative secondary data sources, such as sensors, wearables and mobiles in a standardized structure called Holistic Health Records (HHRs). COMFORTAGE will become a catalyst to help prevent, monitor, and manage progression of age-related diseases and disabilities, especially of dementia and frailty, based on high end research and analysis of the utilization of the aforementioned technologies