Yellow Gold: Innovative systems for sustainable daffodil-derived galanthamine production in the uplands.

加兰他明是一种药品，自1998年以来一直被批准用于治疗阿尔茨海默病。加兰他敏可以化学合成，但这是一个困难和昂贵的过程。用从植物中提取的加兰他敏生产加兰他敏成本效益更高，但供应有限。在英国，水仙花是一种经济上可行的植物种植来源，在高地地区种植水仙花可以使加兰他明的产量提高50%。该提案将提供一种新的生产加兰他明的方法，该方法基于将水仙花种植整合到现有的高地牧场中。这将增加山地农业的经济可持续性，为农民提供高价值的作物，同时在高地地区保持传统的农业系统。该项目将开发所需的机械，量化加兰他敏的产量，并评估将水仙花生产纳入放牧牧场对绵羊生产性能的影响。

Galantamine is a pharmaceutical product that had been an approved Alzheimer’s Disease treatment since 1998. Galantamine can be synthesised chemically but it is a difficult and expensive process. Producing galantamine from galanthamine extracted from plants is more cost effective, but supplies are limited. Daffodils are an economically feasible plant source for cultivation in the UK, and growing daffodils in upland areas triggers a 50% higher yield of galanthamine. This proposal will deliver a new approach for producing galanthamine based on integrating daffodil growing into existing upland pasture. This will increase the economic sustainability of hill farming by providing farmers with a high value crop while maintaining traditional farming systems in the upland areas. The project will develop the required machinery, quantify the yield of galanthamine achievable, and assess the impact on sheep performance of incorporating daffodil production into grazed pastures.