Automated characterisaton of human gene regulatory networks for precision medicine

了解基因调控网络（GRNs）对我们理解细胞功能和疾病至关重要。然而，目前使用基于细胞的检测方法进行GRN表征的实验范式是缓慢、费力和昂贵的，导致低定量分辨率的数据输出有限。在这个项目中，SkyLab Bio用一种不同的方法来解决这些问题。我们将利用最先进的生物系统、自动化和计算来创建高通量、快速、健壮和高度可重复的人体体外GRN原型服务。这将为确定基因调控中的因果关系提供可靠的解决方案，允许对GRN组织进行更定量，无与伦比的洞察。

Understanding gene regulatory networks (GRNs) is critical to our understanding of cellular function and disease. However, the current experimental paradigm of using cell-based assays for GRN characterisation is slow, laborious and costly, resulting in limited data output of low quantitative resolution. In this project, SkyLab Bio confronts these problems using a different approach. We will harness state-of-the-art biological systems, automation and computation to create a high-throughput, rapid, robust and highly reproducible human in vitro GRN prototyping service. This will provide a reliable solution to determining causality in gene regulation, allowing for a more quantitative, unparalleled insight into GRN organisation.