INTERVENTIONS TO REDUCE CANCER RISK AMONG FARM FAMILIES

产品说明： （申请人描述）流行病学证据 继续出现，农民在特定的风险增加， 癌症的类型。 假设主要病原体为 与这些过高的比率有关的是危险化学品， 农民因其职业而面临的风险，即 农药 这些杀虫剂中有许多已被证明是致癌的 在实验室研究中。 其他证据表明， 施用者没有常规地使用必要的预防措施， 保护自己不暴露。 此外，农民及其 家庭是卫生服务不足的人口， 他们的地理和职业地位。 本研究提出 翻译先前的流行病学，实验室，临床， 癌症风险的行为信息纳入初级预防 该计划旨在减少农民及其家庭的癌症。 的 预防性干预措施将针对农药施用者， 他们是农民，他们的家庭通过社区为基础的 旨在增加癌症预防知识的教育计划， 风险认知和自我效能感，以创造行为改变 来降低癌症风险。 农药施用者将被随机 分配给控制或干预条件。 干预组 将接受一项旨在减少个人 农药接触和增加安全的农药处理行为。 农药处理 行为和农药暴露 干预组和对照组将进行6个月和18个月的比较 使用自我报告和生物措施进行干预后。 因为 大多数施用者是男性，因为其他家庭成员 由于生活在农场， 设置，妻子和成年女儿的申请人也将 接受教育干预。 这次干预将是 旨在提高对农药风险的认识， 癌症预防行为，包括乳房自我检查， 在推荐年龄的妇女中进行乳房X光检查。 农场妇女将 接受6个月和12个月的随访，以确定癌症预防 行为改变和维持。 这项研究将在 佛蒙特州是一个以农业为主的州， 在过去的十年里，癌症死亡率过高。

DESCRIPTION: (Applicant's Description) Epidemiologic evidence continues to emerge that farmers are at increased risk for specific types of cancers. The main etiologic agents hypothesized to be connected with these excessive rates are the hazardous chemicals farmers are exposed to by virtue of their occupation, namely pesticides. Many of these pesticides have been shown to be carcinogenic in laboratory studies. Additional evidence suggests that applicators do not routinely use the precautions necessary to protect themselves from exposure. Further, farmers and their families are an underserved population for health services due to their geographic and occupational status. This study proposes to translate prior epidemiologic, laboratory, clinical, and behavioral information on cancer risks into a primary prevention program to reduce cancer among farmers and their families. The preventive interventions will target pesticide applicators, most of whom are farmers, and their families through community-based educational programs designed to increase cancer prevention knowledge, risk perception, and self- efficacy in order to create behavior change to reduce cancer risks. Pesticide applicators will be randomly assigned to a control or intervention condition. The intervention group will receive an educational program designed to decrease personal pesticide exposure and increase safe pesticide handling behaviors. Pesticide handling behaviors and pesticide exposure among intervention and control groups will be compared 6 and 18 months post intervention using self-report and biological measures. Because the majority of applicators are male, and because other family members are likely to be exposed to pesticides by virtue of living in the farm setting, wives and adult daughters of the applicators will also receive an educational intervention. This intervention will be designed to increase knowledge of pesticides risks and increase cancer preventive behaviors including breast self exam and mammography screening among women of recommended age. Farm women will receive a 6 and 12 month follow-up to determine cancer prevention behavior change and maintenance. This study will take place in the state of Vermont, a predominantly rural state that has experienced excessive cancer mortality rates in the previous decade.