CELL COMPARTMENTALIZATION AND VACCINE DEVELOPMENT

这两个并行会议中的每一个，一个集中在细胞上 划分和专注于抗原处理的一个& 开发，将吸引一批认同 各次会议的主要议题。以下是要回答的问题 未来几年的领域包括蛋白质如何整合到 膜系统，这些细胞器如何保持其结构和 功能完整性，并确定负责 分选步骤、细胞器运动和伴随的融合反应 蛋白质转运。最近克隆了编码到MHC区域的基因， 哪些影响多肽运输、蛋白质分解等，给出了线索 免疫系统是如何进化的。剩下的问题是蛋白质是如何 被消化以产生抗原肽，多肽是如何被选择的， 它们是如何与MHC分子结合的，等等。 这两次会议的组织者在处理以下问题时 重视自己的选区，希望汇聚各大 这些领域的贡献者。希望有机会 在正式计划会议之外进行互动，计划出席 联席会议将“正式”地将两组 科学家将鼓励形成新的合作伙伴关系 在不久的将来也将结出硕果的关系 作为知识和技术的即时转移和一种欣赏 关于与这两个相关的成就和挑战 科学领域的努力。

Each of these two concurrent meetings, one focusing on Cell Compartmentalization and one focusing on Antigen Processing & Development, will attract an audience of scientists who identify with the major topics of each conference. Questions to be answered in these fields in the coming years include how proteins become integrated into membrane systems, how these organelles maintain their structural & functional integrity, and identifying the components responsible for the sorting steps, organellar movement & fusion reactions that accompany protein transit. Recent cloning of genes encoded into the MHC region, which effects peptide transport, protein breakdown, etc., gives clues on how the immune system evolved. Questions which remain are how proteins are digested to generate antigenic peptides, how peptides are selected, how they are bound to MHC molecules, etc. The organizers of these two meetings, while addressing issues of importance to their own constituency, hope to bring together major contributors in these fields. It is hoped that the opportunity to interact outside the formal program sessions, the presence of planned joint sessions which will 'formally' bring together both groups of scientists will encourage the formation of new collaborative relationships which will bear fruit in the not too distant future as well as the immediate transfer of knowledge and technique and an appreciation for the achievements and challenges associated with these two related fields of scientific endeavor.