Vaccine Diluent Improvement for ECF-ITM

该项目代表了一个独特的机会，将英国人类卫生部门的技术和专业知识转化为发展中国家的牲畜疾病控制。该项目的重点是东海岸热，这是东非、中非和南部非洲小农户养牛的主要限制因素。一种有效的疫苗，ECF-ITM，目前存在的疾病，但它有一些重要的缺点，影响其在该领域的使用。本项目将试验使用新配方作为ECF-ITM疫苗稀释液的替代品。该项目的成功将带来重要的ECF-ITM疫苗产品增强，特别是疫苗稳定性。这将为ECF疫苗接种人员提供更大的机动性和灵活性，估计每年将有300，000头牛获得有效免疫。这将是该地区小农户牛生产可持续集约化的一个显著发展。财务摘要表为了帮助申请人填写本申请表的财务部分，请参阅申请人指南。它将

This project represents a unique opportunity to translate British technology and expertise from thehuman health sector into livestock disease control in the developing world context. The project focuseson East Coast Fever (ECF), a major constraint on small-holder cattle production in East, Central andSouthern Africa. An effective vaccine, ECF-ITM, currently exists for the disease but it has a number ofimportant drawbacks that affects its use in the field. This project will trial the use of novel formulationsas a replacement for the ECF-ITM vaccine diluent. Success in the project will deliver important ECF-ITMvaccine product enhancements, notably vaccine stability. This will afford far greater mobility andflexibility to ECF vaccinators resulting in an estimated 300,000 additional cattle being effectivelyimmunised per year. This will be a notable development in the sustainable intensification of small-holder cattle production in the region.Finance summary tableTo assist the applicant with the Finance Section of this application form please refer to the Guidance for Applicants. It will