Natural Fatty Aldehydes for Flavours and Fragrances

将对一种新的制造工艺进行评估，以利用可再生原料(种子油加工副产品流)可持续地生产天然醛香料。这些醛染料是香水中最重要的成分之一，也是头发护理产品、清洁、洗衣和个人护理产品中的香气，以及加工食品中的成分。醛还可用作润滑剂、捕虫器、医药、植物生长调节剂、抗菌剂和消毒剂。这些化合物目前是从石化原料中大规模生产的。除了从不可持续的资源中提取之外，石化产品的化学合成还会导致副产品的形成，这些副产品带有难闻的气味，去除起来成本很高，限制了它们的应用。迄今为止，由于化合物对微生物细胞的抑制性质，生物技术生产醛是不可能的。拟议的生产技术将通过开发一种新型酵母将植物脂肪酸转化为有用的醛产品来克服这些挑战。

A new manufacturing process will be evaluated for the sustainable production of natural aldehyde-based flavours and fragrances from renewable feedstocks (seed-oil processing by-product streams). These aldehdyes are among the most important ingredients used in perfumery and as aromas in hair care products, cleaning, laundry, and personal care products, and as ingredients in processed foods. Aldehydes also have applications as lubricants, insect traps, pharmaceuticals, plant growth regulators, antimicrobials and disinfectants. These compounds are currently produced at large scale from petrochemical raw materials. In addition to being derived from unsustainable resources, the chemical synthesis from petrochemicals result in the formation of by-products with unpleasant odours that are costly to remove and which limit their application. Biotechnological production of aldehydes has not been possible to date due to the inhibitory nature of the compounds to microbial cells. The proposed production technology will overcome these challenges by exploiting a novel yeast to convert plant fatty acids to useful aldehyde products.