EASTERN COOPERATIVE ONCOLOGY GROUP

阿尔伯特·爱因斯坦癌症中心一直是，并将继续是 为ECOG提供主要科学资源，为以下项目提供试点研究数据 启动新的ECOG临床试验并提供实验室 相关研究的资源。在过去的资助期内， 淋巴瘤、白血病、乳房、头颈部、黑色素瘤的脑电地形图研究 和胃肠道恶性肿瘤的启动是基于 爱因斯坦。爱因斯坦的两名研究人员已经获得了RO1 为与ECOG临床试验相关的实验室研究提供资金； 爱因斯坦发起了3项基于实验室的相关研究 在白血病中，1例在结肠癌中，1例在宫颈癌中 部分资金由爱因斯坦自己提供。爱因斯坦有 为ECOG开发了3个核心实验室：1)免疫表型 参考实验室；2)与分化相关的分子生物学 维甲酸与白血病；3)白血病bcr-abl的分子生物学 全。爱因斯坦作为三级护理机构，一直保持着它的 应计水平，有167名患者进入(140名来自Main 从1991年7月1日至1992年6月30日)，391名患者继续在 后续行动。40%至52%的患者进入临床试验 来自少数族裔，这在一定程度上反映了爱因斯坦 该机构为招募这类患者进入医院所做的努力 利用少数族裔工作人员鼓励临床研究试验 参与。超过50%的研究参与者是女性，并且 爱因斯坦开发了专门针对恶性肿瘤的ECOG研究 对女人来说。爱因斯坦的一位研究员是妇产科的主席。 工作组。爱因斯坦研究人员主持了13项ECOG研究 在过去的资助期内，爱因斯坦的5名研究人员 疾病或模式委员会的领导角色(主席或联席主席) 在最后一次授权期内。爱因斯坦CGOP，其中包括 另一个主要大学中心(纽约州立大学-斯坦布鲁克分校)和一个大型 长岛医院(拿骚县医疗中心)和 布朗克斯(仁慈的圣母)一直是富有成效的参与者 经社理事会，关于研究和全集团会议的应计费用 出席率。

The Albert Einstein Cancer Center has been and continues to be a major scientific resource for ECOG, providing pilot study data for the initiation of new ECOG clinical trials and providing laboratory resources for correlative studies. During the past grant period, ECOG studies in lymphoma, leukemia, breast, head and neck, melanoma and GI malignancies have been initiated based on pilot work from Einstein. Two of Einstein's investigators have obtained RO1 funding for laboratory research related to ECOG clinical trials, and Einstein has initiated 3 laboratory-based correlative studies in the leukemias, 1 in colon cancer and 1 in cervical cancer with partial funding provided by Einstein itself. Einstein has developed 3 core laboratories for ECOG: 1) immunophenotyping reference lab; 2) molecular biology of differentiation related to retinoic acid in leukemia; and 3) molecular biology of bcr-abl in ALL. Einstein, as a tertiary care facility, has maintained its accrual level, with 167 patients entered (140 from main institution) from 7/1/91 -6/30/92, and 391 patients continuing in follow-up. Forty to 52% of patients entered into clinical trials at Einstein are from minority races which in part reflects the efforts made by the institution to recruit such patients into clinical research trials utilizing minority race staff to encourage participation. More than 50% of study participants are women, and Einstein has developed ECOG studies specifically for malignancies of women. An Einstein investigator is the chair of the Gyn Onc Working Group. Einstein investigators have chaired 13 ECOG studies during the past grant period and 5 Einstein investigators have held disease or modality committee leadership roles (chair or co-chair) during the last grant period. The Einstein CGOP, which includes another major university center (SUNY-Stonybrook) and a large hospital in Long island (Nassau County Medial Center) and one in the Bronx (Our Lady of Mercy) has been productive participants in ECOG, in terms of accrual to studies and groupwide meeting attendance.