LARGE SCALE PREPARATION OF ANTI-AIDS DRUGS

该项目的主要目标是编写已知的 化学品和原料药，这是需要由该计划， 临床应用。 选择用于制备的化合物不 在质量或数量上， 原始供应商或公开市场上。 这个项目提供 获得几乎任何类型的化合物的方法， 能够提供大量非常高来源的药物。 准备材料的数量将由 药物资源分支。 NCI将涉及广泛的 各种化学结构。 许多准备工作将 涉及多步骤序列，所有制备的材料将 完全特征化。

The major objectives of this project is the preparation of known chemicals and bulk drugs which are needed by the program for clinical use. The compounds selected for preparation are not readily available in the quality or quantities required from the original supplier or on the open market. This project provides the means to obtain nearly any type of chemical compound and the ability to provide large quantities of very high originate drugs. Assignments of materials for preparation will originate with the Pharmaceutical Resources Branch. NCI and will involve a wide variety of chemical structures. Many of the Preparations will involve multi-step sequences and all materials prepared will be fully characterized.