CLINICAL CENTER FOR CAMP

主要目的 为了确定，在5-9岁哮喘儿童人群中， 定期使用两类抗炎药物中的任何一种 （吸入性皮质类固醇或克罗埃因钠），与常规 支气管扩张剂药物和彼此，导致更大的肺 功能和更少的支气管高反应性超过五年的时间。 次要目的 为了确定任何一种抗炎药物，与 支气管扩张剂药物和彼此，导致较少的患者 发病率，通过哮喘症状的频率测量，有限的 活动，以及从学校损失的天数。 为了确定是否有任何一种抗炎药物与 定期使用支气管扩张剂药物，并相互使用， 医疗保健资源，如急诊室就诊或 住院治疗 为了比较两类药物的长期安全性和副作用， 与支气管扩张药物相比， 彼此之间 比较两类抗炎药的抗炎作用 与支气管扩张剂药物相比， 身体和心理社会发展以及生活质量。

Primary Objective To determine, in a population of 5-9 year old children with asthma, if regular use of either of two classes of anti-inflammatory medications (inhaled corticosteroids or cromolyn sodium), compared to regular bronchodilator medication and to each other, results in greater lung function and less bronchial hyperresponsiveness over a five year period. Secondary Objectives To determine if either of the anti-inflammatory medications, compared to bronchodilator medication and to each other, results in less patient morbidity, measured by frequency of asthma symptoms, days of limited activity, and days lost from school. To determine if either of the anti-inflammatory medications compared to regular bronchodilator medication and to each other results in less use of health care resources such as emergency room visits or hospitalizations. To compare the long term safety and side effects of the two classes of anti-inflammatory medications, compared to bronchodilator medication and to each other. To compare the effects of the two classes of anti-inflammatory medications, compared to bronchodilator medication and to each other, on physical and psychosocial development, and quality of life.