CONFERENCE ON MUCOSAL IMMUNITY

粘膜免疫系统现在被认为是一个主要的， 免疫系统的一个功能独特的分支， 保护粘膜表面的作用。 最近， 开发新的靶向疫苗的策略， 粘膜诱导位点。 这种发展的一个限制因素 疫苗是我们对细胞和分子 抗原、病原体和疫苗与粘膜细胞的相互作用 组织中 目前的新研究正在解决 抗原、上皮细胞和局部粘膜淋巴细胞和抗原 呈现细胞，对这些事件的新见解正在出现。 一个名为“粘膜免疫： 粘膜细胞和分子的交互作用 将于1997年3月在新墨西哥州圣达菲举行。 拟议中的会议将汇集来自不同领域的科学家 包括细胞和分子免疫学，上皮细胞生物学， 微生物发病机理和疫苗学，重点放在采样 外源抗原和病原体穿过上皮屏障， 粘膜表面的细胞和分子串扰， 保护性免疫反应 最近召开的粘膜相关会议 在过去的两年里，免疫和疫苗的使用范围非常广泛。 范围内。 相比之下，拟议中的基石会议将重点关注 特别是上皮表面的细胞和分子事件 是粘膜免疫反应的基础 由于这种强调 基础科学，吸收年轻科学家参与尤为重要 来自不同学科的培训，他们将成为未来的创新者， 这个快速变化的领域。

The mucosal immune system is now recognized as a major, functionally-distinct branch of the immune system that plays a pivotal role in defense of mucosal surfaces. Recently there has been a surge of interest in developing novel strategies for targeting vaccines to mucosal inductive sites. A limiting factor in the development of such vaccines is our incomplete understanding of the cellular and molecular interactions of antigens, pathogens and vaccines with cells of mucosal tissues. Novel current research is addressing the complex interplay of antigens, epithelial cells, and local mucosal lymphocytes and antigen presenting cells, and new insights into these events are now emerging. A Keystone Conference entitled "MUCOSAL IMMUNITY: CELLULAR AND MOLECULAR CROSS-TALK AT MUCOSAL SURFACES" will be held in March 1997 at Santa Fe, New Mexico. The proposed meeting will bring together scientists from diverse fields including cellular and molecular immunology, epithelial cell biology, microbia pathogenesis and vaccinology, to focus on the sampling of foreign antigens and pathogens across epithelial barriers, and the cellular and molecular cross-talk at mucosal surfaces that leads to protective immune responses. Resent meetings related to mucosal immunity and vaccines held over the past 2 years have been very broad in scope. In contrast, the proposed Keystone Conference will focus specifically on the cellular and molecular events at epithelial surfaces that underlie mucosal immune responses. Because of this emphasis on basic science, it is particularly important to include young scientists in training from diverse disciplines who will be the future innovators in this rapidly-changing field.