PROTEIN LOCALIZATION OF THE YEAST VACUOLE
PROTEIN LOCALIZATION OF THE YEAST VACUOLE
批准号:
2023872
负责人:
BRUCE F HORAZDOVSKY
金额:
$19.09万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-06-01 至 2002-05-31
中文摘要
描述:本研究的长期目标是确定
这些分子事件是溶酶体蛋白质转运到
相当于酵母溶酶体的液泡。 此应用程序侧重于
Ras样GTP酶Vps21p和Sec1同系物Vps45p被证明是重要的
液泡蛋白分选 Horazdovsky博士将精确地定义
这些蛋白质的作用,并开始寻找相互作用的蛋白质,
它们对Vps21p的调节机制。 其他目标包括分析
将携带高尔基体衍生蛋白质的小泡运输到液泡,以及
蛋白酶A分选蛋白的表征。
英文摘要
DESCRIPTION: The long term goal of this research is to determine the
molecular events which underlie the transport of lysosomal proteins to the
yeast lysosome-equivalent, the vacuole. This application focuses on a
Ras-like GTPase, Vps21p, and a Sec1 homolog, Vps45p, shown to be important
in vacuolar protein sorting. Dr. Horazdovsky will define precisely the step
at which these proteins act, and begin to look for interacting proteins and
their mechanisms of modulation of Vps21p. Other aims include analysis of
transport vesicles carrying Golgi derived proteins to the vacuole, and
characterization of the proteinase A sorting proteins.
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会议论文
Institutional Short-Term Research Training for Students of Diversity
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批准号:7474418
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项目类别:
-
资助金额:$9.46万
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财政年份:2008
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
Institutional Short-Term Research Training for Students of Diversity
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批准号:8237047
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项目类别:
-
资助金额:$14.95万
-
财政年份:2008
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
Institutional Short-Term Research Training for Students of Diversity
-
批准号:10410367
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项目类别:
-
资助金额:$16.09万
-
财政年份:2008
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
Institutional Short-Term Research Training for Students of Diversity
-
批准号:8052833
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项目类别:
-
资助金额:$14.95万
-
财政年份:2008
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
Institutional Short-Term Research Training for Students of Diversity
-
批准号:7612709
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项目类别:
-
资助金额:$10.66万
-
财政年份:2008
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
Institutional Short-Term Research Training for Students of Diversity
-
批准号:10606565
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项目类别:
-
资助金额:$16.09万
-
财政年份:2008
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
Institutional Short-Term Research Training for Students of Diversity
-
批准号:7860600
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项目类别:
-
资助金额:$12.55万
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财政年份:2008
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负责人:BRUCE F HORAZDOVSKY
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依托单位:
Cell Surface Receptor Trafficking
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批准号:6914426
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项目类别:
-
资助金额:$24.66万
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财政年份:2003
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负责人:BRUCE F HORAZDOVSKY
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依托单位:
Cell Surface Receptor Trafficking
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批准号:6563013
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项目类别:
-
资助金额:$26.77万
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财政年份:2003
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负责人:BRUCE F HORAZDOVSKY
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依托单位:
Cell Surface Receptor Trafficking
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批准号:7085471
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项目类别:
-
资助金额:$24.08万
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财政年份:2003
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
Cell Surface Receptor Trafficking
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批准号:6766961
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项目类别:
-
资助金额:$24.66万
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财政年份:2003
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负责人:BRUCE F HORAZDOVSKY
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依托单位:
Regulation of intracellular protein traffic
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批准号:7058749
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项目类别:
-
资助金额:$25.98万
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财政年份:1997
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负责人:BRUCE F HORAZDOVSKY
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依托单位:
Regulation of intracellular protein traffic
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批准号:6891345
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项目类别:
-
资助金额:$26.6万
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财政年份:1997
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负责人:BRUCE F HORAZDOVSKY
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依托单位:
PROTEIN LOCALIZATION TO THE YEAST VACUOLE
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批准号:6180661
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项目类别:
-
资助金额:$19.67万
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财政年份:1997
-
负责人:BRUCE F HORAZDOVSKY
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依托单位:
Regulation of intracellular protein traffic
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批准号:6740193
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项目类别:
-
资助金额:$26.6万
-
财政年份:1997
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
PROTEIN LOCALIZATION TO THE YEAST VACUOLE
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批准号:6017100
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项目类别:
-
资助金额:$19.11万
-
财政年份:1997
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
Regulation of intracellular protein traffic
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批准号:6572790
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项目类别:
-
资助金额:$28.88万
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财政年份:1997
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
PROTEIN LOCALIZATION OF THE YEAST VACUOLE
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批准号:2713766
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项目类别:
-
资助金额:$18.57万
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财政年份:1997
-
负责人:BRUCE F HORAZDOVSKY
-
依托单位:
PROTEIN LOCALIZATION TO THE YEAST VACUOLE
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批准号:6386658
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项目类别:
-
资助金额:$20.24万
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财政年份:1997
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负责人:BRUCE F HORAZDOVSKY
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依托单位:
Institutional Short-Term Research Training for Minority
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批准号:6899844
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项目类别:
-
资助金额:$0.0万
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财政年份:1992
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负责人:BRUCE F HORAZDOVSKY
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依托单位: