Does disconnection in the aging brain cause age-related movement decline?

本项目旨在利用新的神经生理学方法来了解与年龄相关的大脑网络连接变化对运动控制的因果作用。大脑区域通过复杂和动态的神经网络相互作用来控制自主运动，但是否与年龄相关的网络连接变化会导致与年龄相关的运动控制能力下降尚不清楚。该项目将提供显著的好处，如开发有针对性的干预措施以改善老年人运动控制所需的神经生理学知识。

This project aims to use new neurophysiological approaches to understand the causal role of age-related changes in brain network connectivity to the movement control. Brain regions interact through complex and dynamic neural networks to control voluntary movement, but whether age-related changes in network connectivity drive age-related decline in movement control is unknown. This project will provide significant benefits such as the neurophysiological knowledge required to develop targeted interventions to improve movement control in the aging population.