DRUG ABUSE PREVENTION AMONG ADOLESCENT WOMEN

这项修订后的第一阶段可行性研究将检查与青春期妇女吸毒有关的社会心理因素。关于这些因素的数据将为制定基于计算机的互动式干预措施提供信息。在为期6个月的过程中，第一阶段将实现三个目标。首先，我们将评估来自纽约市六个社区的84名10至14岁的黑人、拉丁裔和白人青少年妇女的药物滥用行为流行病学及其预防。第二，第一阶段将开发一个交互软件的原型版本，以减少这些年轻女性吸毒和其他物质使用的风险。第三，该研究将通过与纽约市社区网站合作，对270名黑人、拉丁裔和白人年轻女性样本进行初步测试。在随机设计中，先导试验包括两组适度的临床试验。被分配到计算机干预组的年轻女性将与第二阶段开发的原型软件进行交互。控制点的年轻妇女将接受常规的药物意识干预。在干预前后，受试者将完成一系列结果测量。通过实现其目标，第一阶段将为第二阶段奠定基础。这项研究将充分开发一种互动式多媒体产品，以帮助年轻妇女减少吸毒的风险。第二阶段将包括一项随机临床试验，在大纽约市不同社区的年轻女性中测试开发的软件。如果第二阶段的软件取得成功，第三阶段将把互动程序商业化，并向参与该研发项目的学校、医疗机构和社区机构传播。拟议的商业应用：这项研究的数据将揭示年轻女性使用毒品和其他物质的原因，以及计算机干预如何帮助她们预防这种使用。通过明确设计和互动内容对年轻妇女进行干预，有望触及和影响迄今为止在药物滥用预防研究中被忽视的高危人群。

This revised Phase I feasibility study will examine psychosocial factors associated with drug use among adolescent women. Data on those factors will inform the development of an interactive computer-based intervention. Over the course of its 6 months, Phase I will accomplish three aims. First, we will assess the behavioral epidemiology of drug abuse and its prevention among a total sample of 84 Black, Latina, and white adolescent women, aged 10 to 14 years, from six community sites in New York City. Second, Phase I will develop a prototype version of interactive software to reduce the risks of drug and other substance use among those young women. Third, the study will pilot test the prototype interactive software with a sample of 270 Black, Latina, and white young women through the auspices of collaborating New York City community sites. In a randomized design, the pilot test involves a modest clinical trial with two arms. Young women in sites assigned to the computer intervention arm will interact with prototypic software developed in Aim 2. Young women in control sites will receive conventional drug awareness intervention. Before and after intervention, subjects will complete a battery of outcome measures. By meeting its aims, Phase I will lay a foundation for Phase II. That research will fully develop an interactive multimedia product to help young women reduce their risks for drug use. Phase II will include a randomized clinical trial to test the developed software with young women from various community settings in greater New York City. If Phase II software proves successful, Phase III will commercialize and disseminate the interactive program to schools and health care facilities and such community agencies as engaged in this R&D project. PROPOSED COMMERCIAL APPLICATION: Data from this study will shed empirical light on why young women use drugs and other substances and on how computer-mediated interventions can help them prevent that use. Intervening with young women via expressly designed and interactive content holds promise for reaching and impacting an at-risk population heretofore neglected in drug abuse prevention research.