COMMUNITY CLINICAL ONCOLOGY PROGRAM RESEARCH BASE

描述：（申请人的描述）放射治疗肿瘤组 （RTOG）致力于成为社区临床研究基地 肿瘤学计划（CCOP）。 本申请记录了目前的RTOG癌症 CCOP的25个成员参加的控制组织， 癌症治疗研究和癌症预防与控制领域 科学建议。 RTOG凭借其在以下方面的经验和专业知识， 地方区域癌症治疗和控制，将继续利用 CCOP网络作为其癌症控制研究的主要组成部分之一 该计划的重点是在治愈和潜在的干预研究 可治愈的癌症患者 本申请记录了癌症预防 在RTOG内的控制活动， 化学预防经验计划，批准和建议的干预措施 头颈癌、脑癌和胃肠癌的研究，以及 针对症状控制的研究。 为了满足癌症扩大的需要， 控制程序，并完成CCOP成员的整合， RTOG，癌症控制副主席和CCOP主要研究者 (PI)委员会主席已成立，以协调预防癌症 化学预防、迟发效应、 生命、流行病学和特殊人群委员会，以及 生物统计、经济影响和研究助理支助单位。 一 指导委员会，由被指定参加这些委员会的委员会成员组成， PI主席和癌症控制副主席，评估并设置 所有癌症预防和控制研究的优先事项。 CCOP是 由CCOP成员评估委员会评估，以确保遵守 所有NCI要求。 管理、方案、质量保证和 RTOG的数据管理单元用于启动这些癌症 对照试验和质量保证程序，包括现场 审计，适用于社区网络。 目标是继续 将CCOP整合到RTOG中，以确保所有成员都有机会 参与RTOG活动的所有事实，以促进 将最新的科学信息传递到社区。

DESCRIPTION: (Applicant's Description) The Radiation Therapy Oncology Group (RTOG) has committed itself as a Research Base for the Community Clinical Oncology Program (CCOP). This application documents the current RTOG cancer control organization within which the 25 CCOP members participate in the areas of cancer treatment studies and cancer prevention and control scientific proposals. The RTOG, with its experience and expertise in local-regional cancer treatment and control, will continue to utilize the CCOP network as one of the major components of its cancer control research program, which focuses on intervention studies in the cured and potentially curable cancer patient. This application documents the cancer prevention and control activity within the RTOG manifested by the established chemoprevention experience program, the approved and proposed intervention studies in head and neck, brain and gastrointestinal cancers, as well as studies addressing symptom control. To meet the needs of an expanded cancer control program and to complete the integration of CCOP members into the RTOG, a Vice Chair for Cancer Control and a CCOP Principal Investigators' (PI) Committee Chair have been established to c o ordinate cancer prevention and control activities within the Chemoprevention, Late Effects, Quality of Life, Epidemiology and Special Populations Committees, as well as Biostatistics, Economic Impact and Research Associates support units. A Steering Committee composed of CCOP designees to these committees, the CCOP PI's Chair and the Vice Chair for Cancer Control, evaluate and set priorities for all cancer prevention and control studies. The CCOPs are evaluated by the CCOP Membership Evaluation Committee to insure adherence to all NCI requirements. The Administrative, Protocol, Quality Assurance and Data Management Units of RTOG are utilized in initiating these cancer control trials and the quality assurance procedures, including on-site audits, are applied to the community network. The goal is for the continued integration of the CCOPs into the RTOG to insure all members the opportunity to participate in all facts of RTOG activities in order to facilitate the transference of the latest scientific information into the community.