NEURAL SYSTEMS AND BEHAVIOR

自1978年以来，神经系统和行为（NS和B）夏季课程在 海洋生物实验室一直在提供强化培训， 现代行为神经生物学的概念和方法， 早期阶段的优秀博士前和博士后学生 研究生涯。 20名学生沉浸在8周的讲座中 在一些最好的老师的指导下进行实验室工作 和研究人员在该领域，由邀请研讨会发言人， 驻校学者。 这种高度集成和互动的形式 在标准的大学培训中很少有。 学生来 来自不同的背景，包括神经科学，生物学，心理学， 医学、数学、物理学和工程学。 新的联合董事， 在1995年担任课程的领导， NS和B的核心优势，同时纳入新的练习， 教师。 广泛的实验室实践培训， 设备包括各种无脊椎动物和脊椎动物 准备工作 实验室部分，分为4个2周 周期从基本的电生理技术开始。学生 然后继续研究神经调节和重构， 神经回路，听觉信息的接收和处理 在三个互补的准备工作中进行了研究， 在行为、神经元群体和突触水平上进行了研究。 在 除了传统的电生理技术，学生们还学习 贴片和全细胞记录，定量行为分析， 正常和基因敲除小鼠，多电极记录从自由- 行为啮齿动物在空间学习，在原位细胞内 脊椎动物脑记录，脑切片记录，计算 复杂系统的方法，计算机化数据采集和 分析、细胞培养记录和神经解剖技术 包括原位杂交。 过去的课程评价， 最近的NS和B校友/AE表明，该课程非常有效 在准备学生的创造性和生产性的研究生涯， 神经生物学和行为学。 要求提供资金，以继续这一独特的 以目前的形式进行培训。

Since 1978, the Neural Systems and Behavior (NS and B) summer course at the Marine Biological Laboratory has been providing intensive training in the concepts and methodology of modern behavioral neurobiology to outstanding pre- and postdoctoral students during early stages of their research careers. Twenty students are immersed for 8 weeks in lectures and laboratory work under the mentorship of some of the best teachers and researchers in the field, augmented by invited seminar speakers and Scholars-in-Residence. This highly integrated and interactive format is rarely available during standard university training. Students come from diverse backgrounds including neuroscience, biology, psychology, medicine, mathematics, physics and engineering. New Co-Directors who assumed leadership of the course in 1995 have maintained the traditional core strengths of NS and B while incorporating new exercises and faculty. Extensive hands-on laboratory training with state-of-the-art equipment includes a variety of invertebrate and vertebrate preparations. The laboratory section, which is divided into four 2-week Cycles begins with fundamental electrophysiological techniques. Students then move on to investigate neuromodulation and reconfiguration of neural circuits, the reception and processing of auditory information studied in three complementary preparations, and learning and memory studied at the behavioral, neuronal population and synaptic levels. In addition to conventional electrophysiological techniques, students learn patch and whole-cell recordings, quantitative behavioral analyses of normal and knockout mice, multi-electrode recordings from freely- behaving rodents during spatial learning, in situ intracellular recording from vertebrate brain, brain slice recordings, computational approaches to complex systems, computerized data acquisition and analysis, cell culture recordings, and neuroanatomical techniques including in situ hybridization. Course evaluations from past and recent NS and B alumni/ae suggest that the course is highly effective in preparing students for creative and productive research careers in neurobiology and behavior. Funding is requested to continue this unique training opportunity in its present form.