课题基金 / 基金详情

EFFECTS OF MATERNAL PHENYLKETONURIA ON PREGNANCY OUTCOME

EFFECTS OF MATERNAL PHENYLKETONURIA ON PREGNANCY OUTCOME
母亲苯丙酮尿症对妊娠结局的影响
批准号：
2793788
负责人：
BOBBYE M ROUSE
金额：
$10.6万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
1992
资助国家：
美国
项目状态：
已结题
起止时间：
1992-06-23 至 1999-06-22
来源：
https://reporter.nih.gov/project-details/2793788
关键词：
behavior test behavioral /social science research tag birth child physical development child psychology clinical chemistry dietary aminoacid dietary control female human genetic material tag human subject hyperphenylalaninemia longitudinal human study nervous system disorder diagnosis nutrition related tag patient /disease registry phenylketonurias pregnancy psychometrics socioeconomics socioenvironment ultrasonography

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中文摘要
翻译
该项目的主要目的是确定最佳方法， 妊娠期高苯丙氨酸血症（HPA）的管理 包括：经典苯丙酮尿症（PKU）-血苯丙氨酸 正常饮食时浓度超过20 mg/dl;变异PKU - 10-20 mg/dl;或良性HPA - 4-10 mg/dl。 胎儿发病率， 与孕产妇死亡有关的生长和发育问题 将评估PKU与母体苯丙氨酸水平的关系。
英文摘要
The primary purpose of this project is to determine the best method of managing women during pregnancy who have hyperphenylalaninemia (HPA) including: classical phenylketonuria (PKU) - blood phenylalanine concentrations of more than 20 mg/dl while on a normal diet; variant PKU - 10-20 mg/dl; or benign HPA - 4-10 mg/dl. Fetal morbidity, with subsequent problems in growth and development, associated with maternal PKU will be assessed in relation to maternal phenylalanine levels.
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