SOLID STATE DETECTOR FOR GAS CHROMATOGRAPHY

使用放射性标记化合物的毛细管柱气相色谱法是一种 分析化学中的重要工具，但其性能，特别是 低能量β粒子，受到辐射探测器的限制 目前正在使用。我们建议开发一个基于固体的系统， 该传感器将提供极高的灵敏度， 妥协的解决方案。我们将使用avalanche来实现这一点 光电二极管（APD），已经证明能够检测低 能量β粒子，包括来自氚的能量β粒子，具有高效率。 APD是用于这种辐射的上级传感器，因为它可以由 一个非常薄的前窗口，并具有内部增益，以提供非常高的 信号噪声比。此外，APD结构紧凑， 在毛细管柱气相色谱法中的分辨率， 阵列，允许非常高的灵敏度为小样本。 第一阶段的研究工作已顺利完成， 技术目标已经实现。第一阶段证明，APD可以 其制造效率超过任何其他固态 检测器在第二阶段，研究将继续进行并扩大到 包括制造完整的检测器系统， 加入气相色谱仪。

Capillary column gas chromatography using radiolabelled compounds is an important tool in analytical chemistry, but its performance, especially with low energy beta particles, is limited by the radiation detectors which are currently used. We propose to develop a system based on solid state sensors which will provide extremely high sensitivity without compromising resolution. We will accomplish this using avalanche photodiodes (APDs), which have demonstrated the ability to detect low energy beta particles, including those from tritium, with high efficiency. An APD is a superior sensor for such radiation because it can be made with a very thin front window and has internal gain to provide a very high signal-to-noise ratio. Moreover, APDs are compact, allowing good resolution in capillary column gas chromatography and can be made in arrays, allowing very high sensitivity for small samples. The research in Phase I was completed successfully and all of the technical goals were met. Phase I demonstrated that APDs could be fabricated with efficiencies exceeding those of any other solid state detector. In Phase II, the research will be continued and expanded to include the fabrication of complete detector systems suitable for incorporation into gas chromatography instruments.