HOME BASED MODERATE EXERCISE FOR BREAST CANCER PATIENTS

描述：为成长中的儿童提供康复的创新疗法 迫切需要大量的癌症幸存者。乳腺癌患者 已经完成癌症的治疗，有相当的经验 心理困扰(如焦虑、抑郁、身体形象不佳)，以及 可持续数年的疲劳和体重增加的身体症状 后处理。随着存活率的提高，这些心理社会 困难更加突出。调查人员提议提供 早期乳腺癌幸存者的创新治疗计划 改善一些伴随而来的生理和心理症状 癌症诊断和治疗，并促进恢复生活任务。 其他人群的运动参与度已经被证明减少了 情感苦恼，改善身体形象，增加赋能感，以及 减少疲劳和体重增加。 这项研究建议研究以家庭为基础的适度的 乳腺癌幸存者的锻炼计划以及这些计划的好处 妇女可以从参加这样的项目中受益。一百和 34名早期乳腺癌患者(0、I、II期) 在过去两年内确诊)已完成手术和辅助治疗 治疗将被邀请参加。受试者将被随机分配到 为期12周的家庭锻炼计划或接触控制条件。 参与者将被要求完成标准化的锻炼措施， 情绪、生活质量、躯体症状、身体形象和应对方式 治疗12周、6个月、9个月(随访3个月、6个月)。 锻炼参与度将通过自我报告和Caltrac进行衡量 加速计。12分钟的步行测试将在预处理和 在12周时。协方差分析将用于评估治疗 将使用影响和回归分析来确定哪些类型的 患者从这一独特的癌症康复计划中受益。 通过评估家庭锻炼计划对运动质量的影响 癌症幸存者的生活和情绪，这项研究可以作为 研究运动对生活质量和癌症的长期影响 复发。这项研究还提出了有趣的可能性 阐明运动对激素和免疫的生理影响 与乳腺癌有关的机制。

DESCRIPTION: Innovative treatments for the rehabilitation of the growing number of cancer survivors are sorely needed. Breast cancer patients who have completed medical treatment for cancer experience considerable psychological distress (e.g., anxiety, depression, poor body image), and physical symptoms of fatigue and weight gain that can last several years post-treatment. With increased survival rates, these psychosocial difficulties have become more salient. The investigators propose to offer early-stage breast cancer survivors an innovative treatment program to ameliorate some of the physical and psychological symptoms that accompany cancer diagnosis and treatment, and to facilitate resumption of life-tasks. Exercise participation in other populations has been shown to reduce affective distress, improve body image, increase sense of empowerment, and reduce fatigue and weight gain. This study proposes to examine the feasibility of a home-based moderate exercise program among breast cancer survivors and the benefits that these women could gain from participating in such a program. One hundred and thirty-four women with early-stage breast cancer (Stages 0, I and II diagnosed within the past two years) who have completed surgery and adjuvant therapy will be invited to participate. Subjects will be randomized to a 12-week home-based exercise program or a contact control condition. Participants will be asked to complete standardized measures of exercise, mood, quality of life, physical symptoms, body image and coping before treatment, at 12 weeks, 6 months and 9 months (3 and 6 month follow-ups). Exercise participation will be measured by self-report and by Caltrac accelerometers. A 12-minute walk test will be conducted at pretreatment and at 12 weeks. Analyses of covariance will be used to assess treatment effects and regression analyses will be used to determine which types of patients benefit from this unique cancer rehabilitation program. By evaluating the effects of a home-based exercise program on quality of life and mood in cancer survivors, this study can serve as a precursor to examining the long-term effects of exercise on quality of life and cancer recurrence. This study also raises the intriguing possibility of elucidating the physiological effects of exercise on hormonal and immune mechanisms involved in breast cancer.