FASEB CONFERENCE--NEURAL MECHANISMS IN CARDIOVASCULAR RE

本次会议将是FASEB致力于循环神经控制系列会议的第七次会议。由于其与心律失常、心脏疼痛、高血压、脊髓损伤后自主神经亢进、睡眠呼吸暂停等主要病理生理问题相关，这一主题越来越受到关注。这次会议的主要目的是让科学家和临床研究人员在一周的时间里专注于神经控制循环的密切相关方面。这次会议应有助于开辟新的研究领域，并对以前接受的想法进行有意义的重新审查。细胞和分子技术的最新进展正在对这一非常复杂的综合生理学领域产生影响。这一点在1994年和1996年会议上的许多发言中都很明显。下一个项目将继续在细胞和分子技术方面有坚实的代表，这些技术最有可能为神经科学的这一分支提供新的突破。然而，我们将继续大力强调综合生理学方法，为解释临床问题和潜在的药物干预策略提供基本概念。会议将安排9个全体会议，每个会议由4个报告组成，其间有充足的讨论时间。以下主题将涉及：心脏疼痛/传入机制和中枢处理；脊髓损伤后自主神经功能障碍；长期动脉压控制的神经源性模型；发热时的自主神经反应模式；髓质缝在心血管和伤害性调节中的作用睡眠和觉醒期间的心血管调节及其与心血管疾病的联系；运动时循环的神经调节；心血管调控的分子和遗传学研究咪唑啉受体及其内源性配体在血压控制中的作用。提议的37位发言人已正式同意参加。海报会议和选定学生的海报展示将完成正式的日程安排，其余时间用于非正式的互动。

The proposed conference will be the seventh in a series of FASEB Meetings dedicated to the Neural Control of Circulation. This topic is of ever increasing interest because of its relevance to major pathophysiological problems such as dysrhythmias, cardiac pain, hypertension, autonomic hyperactivity after spinal cord injury, sleep apnea etc. The main objective of the planned conference is to allow scientists and clinicians investigators to focus on closely interrelated aspects of the neural control of circulation for a week. This conference should help to open new areas of research and to provide a meaningful reexamination of previously accepted ideas. The recent advances in cellular and molecular techniques are making their impact in this very complex area of integrative physiology. This was evident in many of the presentations at the 1994 and 1996 conferences. The next program will continue to have a solid representation in cellular and molecular techniques that are most likely to provide new breakthroughs in this branch of neuroscience. However, we will maintain a vigorous emphasis on integrative physiological approaches which provide essential concepts to interpret clinical problems and potential strategies for pharmacological intervention. The conference will be organized around 9 plenary sessions each consisting of 4 presentations with ample time for discussion in between. The following topics will be covered: cardiac pain/afferent mechanisms and central processing; autonomic dysfunction after spinal cord injury; neurogenic models of long- term arterial pressure control; patterned autonomic responses during fever; role of medullary raphe in cardiovascular and nociceptive modulation; cardiovascular regulation during sleep and arousal and links to cardiovascular disease; neural regulation of circulation during exercise; molecular and genetic approaches to the study of cardiovascular regulations; imidazoline receptors and their endogenous ligands in the control of blood pressure. The 37 proposed speakers have already formally agreed to participate. Poster sessions and a poster presentation by selected students will complete the formal schedule, the rest of the time being dedicated to informal interactions.