Immunisation to protect against transmissible cancers in Tasmanian devils
Immunisation to protect against transmissible cancers in Tasmanian devils
批准号:
DP180100520
负责人:
Prof Gregory Woods
金额:
$21.24万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-07-14 至 2021-12-31
中文摘要
该项目旨在确定可传播癌症--魔鬼面部肿瘤疾病(DFTD)为避免被免疫系统杀死而使用的免疫逃逸机制。由于第二种可传染癌症(DFT2)的发现围绕着魔鬼免疫系统是否能对这种癌症做出反应,因此该项目将研究对DFT2的免疫反应。最终目标是开发一种疫苗,具有保护健康魔鬼和治愈患有DFTD的魔鬼的潜力。
英文摘要
This project aims to identify the immune escape mechanisms that the transmissible cancers, Devil Facial Tumour Disease (DFTD) use to avoid being killed by the immune system. Since the discovery of the second transmissible cancer (DFT2) mystery surrounds whether the devils immune system can respond to this cancer, hence this project will investigate the immune response to DFT2. The final aims are to develop a vaccine with the potential to protect healthy devils and cure devils with DFTD.
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会议论文
Development of an immune enhancing vaccine to protect Tasmanian devils against a contagious cancer
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批准号:LP130100218
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项目类别:Linkage Projects
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资助金额:$29.66万
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财政年份:2014
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负责人:Prof Gregory Woods
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依托单位:
Host-tumour interplay in Tasmanian devils with devil facial tumour disease: can immune cells be harnessed for therapy?
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批准号:DP130100715
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项目类别:Discovery Projects
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资助金额:$27.0万
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财政年份:2013
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负责人:Prof Gregory Woods
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依托单位:
An immunological and immunogenetic approach to understand and to protect Tasmanian devils against Devil Facial Tumour Disease
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批准号:LP0989727
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项目类别:Linkage Projects
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资助金额:$27.72万
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财政年份:2009
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负责人:Prof Gregory Woods
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依托单位:
Combined application: Dr Woods and Ms Doherty
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批准号:nhmrc : 106914
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项目类别:NHMRC Project Grants
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资助金额:$22.84万
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财政年份:2001
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负责人:Prof Gregory Woods
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依托单位:
海外基金