FUNCTIONAL ORGANIZATION AND CONTROL OF HUMAN MASSETERS

我的长期职业目标包括（1）保持 一个在咀嚼领域富有成效和有意义的研究计划 对学生的教学产生积极的影响 采用多学科方法（基础科学和临床科学）;以及 (3)提供最有效的评估和治疗服务 我们目前所知的病人 在这两个方面都有坚实的基础 在基础科学和临床领域，培养有意义的能力 假设并在科学基础上对其进行适当的检验 增强 因此，我的近期职业目标是 扩展我在神经生理学领域的基础知识，以及更多 特别是在电动机控制机构领域。 柬埔寨皇家民防部队将 提供一种机制：（1）发展基本背景;（2） 学习动物实验技术;（3）学习 哺乳动物肢体运动控制机制的直接参与 在三个实验室进行的NIH资助的研究以及休假 （三）加强大学内外的跨学科交流 在基础和临床科学的最终目标 运用这一更广泛的知识基础 与健康有关的问题。 集成了来自 佛罗里达大学（约翰·曼森博士）和埃默里大学（A.W. 英语和T. R.博士Nichols）将在以下方面提供丰富的经验： 神经再生后的运动控制区域，发育方面 神经肌肉区室的功能，以及姿势和僵硬的调节 以及它们与肌肉长度和力量变化、皮肤输入的关系 和脑干结构。 另外，在休假六个月 在RCDA期限结束时在另一个机构进行的交易将进一步 拓宽我的背景。 我会考虑那些有专业 研究集中在咀嚼系统。 拟进行的研究 在非正式培训的同时，还将检查 解剖学基础、功能组织和控制机制 的人咬肌（类似于博士的研究。英语 在猫后肢中）。 一个合乎逻辑的进程之后将是 检查咬肌内部解剖结构以识别其 结构分区，然后研究功能神经肌肉 通过多部位EMG记录来确定肌肉的隔室。 经过全面 正常人咬肌功能组织的评价 受试者无疼痛，我们将检查无症状受试者 实验引起的面部疼痛。

Long term career objectives of mine consist of (1) maintaining a productive and meaningful research program in the area of masticatory motor control; (2) having a positive impact on the teaching of students by utilizing a multi-disciplinary approach (basic and clinical sciences); and (3) providing the most effective evaluation and treatment services to patients based on our current knowledge. With a firm foundation in both the basic sciences and clinical fields, the ability to develop meaningful hypotheses and test them appropriately on a scientific basis may be enhanced. My immediate career objective, therefore, is to refine and extend my basic knowledge in the field of neurophysiology, and more specifically, in the area of motor control mechanisms. The RCDA would provide a mechanism for: (1) developing the fundamental background; (2) learning laboratory techniques for animal investigations; (3) learning mammalian motor control mechanisms in the limb by direct participation in on-going NIH funded research in three laboratories as well as a sabbatical outside the University; and ) increasing the interdisciplinary exchange of ideas in the basic and clinical sciences with the ultimate objective of applying this broader base of knowledge towards investigating health-related problems. An integration of the expertise from the University of Florida (Dr. John Munson) and Emory University (Dr. A.W. English and Dr. T.R. Nichols) will provide a substantial experience in the area of motor control following nerve regeneration, developmental aspects of neuromuscular compartments, and the regulation of posture and stiffness and their relationship to muscle length and force changes, cutaneous inputs and brainstem structures. In addition, spending a six month sabbatical near the end of the RCDA period at another institution would further broaden my background. I would consider laboratories which have a major research focus on the masticatory system. The research to be conducted in parallel to the informal training will examine the basic fundamentals of the anatomical substrate, functional organization and mechanisms of control of the human masseter muscle (similar to the studies of Dr. A.W. English in cat hindlimb). A logical progression will be followed by first examining the masseter internal anatomical architecture to identify its structural partitions, and then study the functional neuromuscular compartments of the muscle by multi-site EMG recordings. After a thorough evaluation of the functional organization of the masseter muscle in normal subjects without pain, we will examine asymptomatic subjects with experimentally-induced facial pain.