METHADONE MAINTENANCE DETOX OUTCOME--ROLE OF DETOX FEAR

美沙酮维持治疗病人完成 戒毒和开始一个无药物的调整是小于 在结果研究中为50%，完成率为19%。 研究 这里提出的直接影响和实际应用， 改善解毒效果。 由于维修是第一次 使用，调查人员发现增加焦虑的前景， 解毒 Cushman和多尔（1973年）发现， 戒毒康复者中 因为焦虑增加。 调查人员随后 确定了解毒恐惧的相关因素，并制定了可靠的 和有效的措施，怀疑它是罪魁祸首之一， 维持排毒效果差。 但迄今为止， 解毒恐惧在解毒中作用的直接证据 结果。 我们将跟踪一个随机抽样队列的271名治疗成瘾者在3 从我们以前的研究和发现大型维护计划 他们的美沙酮维持和戒毒结果。 我们将 确定那些先前确定解毒的人是否害怕 在完成解毒过程中表现出预期的困难。 我们将 通过现场详细的图表审查和个人 与留下的受试者的访谈。 我们将 仔细评估恐惧主题，以确定他们是否没有 接受治疗，并分别分析数据 从那些有。 研究者的假设是否 这项研究将提供科学上有用的美沙酮 维持和解毒结果数据的大型随机 来自3个地理、文化和 不同种族的亚群。

Prospects for methadone maintenance patients completing detoxification and initiating a drug-free adjustment are less than 50% in outcome studies and completion rates range to 19%. Research proposed here has direct implications and practical application for improving detoxification outcome. Since maintenance was first used, investigators discovered increased anxiety at prospects of detoxification. Cushman and Dole (1973) found 11% of their sample of rehabilitated maintenance patients aborted detoxification because of increased anxiety. Investigators subsequently identified detoxification fear's correlates and developed reliable and valid measures for it, suspecting it as one of the culprits in poor maintenance detoxification outcome. But to date we have no direct evidence of detoxification fear's role in detoxification outcome. We will follow a random sample cohort of 271 treated addicts in 3 large maintenance programs from our previous research and discover their methadone maintenance and detoxification outcome. We will determine if those with previously identified detoxification fear show expected difficulty in completing detoxification. We will accomplish this through on site detailed chart reviews and personal interviews with fear subjects from the cohort who remain. We will carefully assess fear subjects to determine if they have not received treatment for their fear and analyze the data separately from those who have. Whether or not investigators' hypotheses are supported, the study will provide scientifically useful methadone maintenance and detoxification outcome data on a large random sample of treated patients from 3 geographically, culturally and racially different subpopulations.