QUANTITATIVE STUDIES OF VISUAL PATHWAYS IN PRIMATE

总体目标是了解中枢视觉通路是如何 分析有关颜色和空间属性的信息 物体。提出了五个项目，所有这些项目都旨在 阐明颜色视觉与其潜在的联系 生理学。这项工作既包括生理实验，也包括 猕猴(外侧膝状体记录)的研究 (LGN)，纹状皮质和皮质区V2和V4)和 在人体上的心理物理实验，我将在所有这些实验中 测量对彩色电视上显示的图案的灵敏度 监视器。 第一个项目将研究色度的多路传输。 在LGN的小细胞层的神经元中可以看到信号。能不能 看到神经元完成这一双重任务的感知迹象，并可以 彩色信号和非彩色信号的区别在于 细胞的放电模式？第二个项目将检查 颜色适应的受体后机制的作用。 他们有几个吗？他们是不是根据他们的 色度或时间属性，以及在视觉中的位置 他们会撒谎吗？第三个项目将检查 纹状体和纹外皮质神经元的可靠性 可以区分色调，并将检查可能 产生在一些神经元中看到的对色调的尖锐调整。这个 第四个项目将考察同步对比的作用 (色度感应)，并将研究其可能性 生理底物。最后的项目将考察 纹外皮质神经元可能在颜色中起作用 坚定不移。它们如何权衡来自不同 感受野的部分，以及它们的敏感度是如何调节的 通过累积的信号？

The overall aim is to understand how central visual pathways analyze information about the chromatic and spatial properties of objects. Five projects are proposed, all of which are intended to explicate the links between color vision and its underlying physiology. The work involves both physiological experiments and on macaque monkey (recording from Lateral Geniculate Nucleus (LGN), striate cortex an cortical areas V2 and V4) and psychophysical experiments on human, in all of which I shall measure sensitivity to patterns displayed on a color television monitor. The first project will investigate the multiplexing of chromatic signals seen in neurons in parvocellular layers of LGN. Can one see perceptual signs of this double-duty done by neurons, and can the chromatic and achromatic signals be distinguished in the discharge patterns of cells? The second project will examine the action of post-receptoral mechanisms of chromatic adaptation. Are there several of them, are they distinguished by their chromatic or temporal properties, and where in the visual pathway do they lie? The third project will examine the reliability with which neurons in striate and extrastriate cortex can distinguish hues, and will examine mechanism that could produce the sharp tuning for hue seen in some neurons. The fourth project will examine the role of simultaneous contrast (chromatic induction) and will investigate its possible physiological substrates. The final project will examine whether neurons in extrastriate cortex could play a role in color constancy. How do they weigh chromatic signals from different parts of the receptive field, and how is their sensitivity regulated by the accumulated signal?