SES, JOHN HENRYISM AND HYPERTENSION-RISK IN BLACKS

这项拟议的研究是对社会、饮食和 血压变化的人体测量学预测指标 经济多元化的南方黑人人口。研究参与者(665人 男性，1119名女性)在1988年，也就是 基线调查，居住在北卡罗来纳州皮特县。这个社区是 美国东南部的一个地区，众所周知，从 冠心病和中风。将努力重新采访 1429名受访者(571名男性，912名女性)未经治疗，平均舒张期 血压在基线时为95毫米汞柱，在随访时再次变化。 其间4-5年(1988-1992/93)的血压将为 检查过了。社会变量包括社会经济地位(SES)，约翰 亨利主义、压力和社会支持；饮食变量包括 酒精、钠、钾和钙；以及人体测量变量 包括体重指数(BMI)和腰臀比(WHR)。重点强调 在社会经济状况、体育活动、饮食习惯和吸烟方面， 体重增加的预测指标和身体脂肪模式的变化也将 接受检查。多元线性回归将成为主要的分析工具 用来研究这些纵向关系。在横截面上 分析控制体力活动和其他重要变量的因素， 胰岛素抵抗在肥胖之间的中介联系中的作用 此外，还将检查血压、压力和血压。 因此，本研究旨在澄清社会、社会和文化之间的相互关系， 美国黑人高血压的行为和生物学决定因素。 研究结果将用于规划临床和公共卫生 对这一人群和其他类似高危黑人人群的干预。

The proposed study is a longitudinal investigation of social, dietary, and anthropometric predictors of changes in blood pressure in a large, economically diverse southern, Black population. Study participants (665 men, 1,119 women) were between 25-50 years of age in 1988, the year of the baseline survey, and resided in Pitt County, NC. This community is part of a region in the southeastern U.S. known to have elevated mortality from coronary heart disease and stroke. Efforts will be made to re-interview the 1,429 respondents (571 men, 912 women) with untreated, mean diastolic blood pressure < 95 mmHg at baseline, and again at follow-up, on changes in blood pressure during the intervening 4-5 years (1988-1992/93) will be examined. The social variables include socioeconomic status (SES), John Henryism, stress, and social support; the dietary variables include alcohol, sodium, potassium, and calcium; and the anthropometric variables include body mass index (BMI) and waist/hip ratio (WHR). With an emphasis on SES, physical activity, dietary habits, and cigarette smoking, the predictors of weight gain, and changes in patterning of body fat will also be examined. Multiple linear regression will be the primary analytic tool used to study these longitudinal relationships. In cross-sectional analyses which control for physical activity and other important variables, the role of insulin resistance in mediating associations between obesity and blood pressure, and stress and blood pressure, will also be examined. Thus this study aims to clarify interrelationships among social, behavioral, and biological determinants of hypertension in Black Americans. Study findings will be used to plan clinical and public health interventions in this and other similarly high risk Black populations.