ENDOCRINE DETERMINANTS OF SEXUAL BEHAVIOR AND AROUSAL

本申请旨在阐明与之相关的犯罪行为关系 与雌性恒河猴的社会性行为有关。 一 该提案的突出特点是包括遥测 生殖道结构、心脏、 率，和呼吸频率的女性暴露于四个不同的 性刺激的评估测试。 使用所述生理 信息，生理性唤起的定量指标将是 构建了 该指数将用于检查个体差异 在选定的女性中， 接受行为 内分泌因素（雌二醇和睾酮）将 监测和/或给药以确定它们对生理的影响， 性唤起，以及性唤起和感知能力之间的关系， 接受性 该项目的目标有三个方面：（1）促进 关于内分泌的“APR”（吸引-感知-接受）理论 社会性行为的中介; 2）将心理物理 性唤起的表现，以公开的行为和概念， 感知和接受能力; 3）开始系统的方法， 性唤起功能障碍的问题，通过使用现有的范围， 雌性恒河猴的个体差异。 最终临床获益 包括确定和治疗特定类型性侵犯 功能障碍，并进一步澄清性之间的关系， 唤醒和支配/攻击表现。

This application seeks to clarify hormone-behavior relationships associated with the display of sociosexual behavior in female rhesus monkeys. A prominent feature of the proposal is the inclusion of telemetrically signalled somatic-visceral responses of genital tract structures, heart rate, and respiration frequencies of females exposed to four differing assessment tests of sexual stimulation. Using the physiological information, a quantitative index of physiologic sexual arousal will be constructed. The index will be used to examine individual differences among selected females with regard to the display of proceptive and receptive behavior. Endocrine factors (estradiol and testosterone) will be monitored and/or administered to determine their effects on physiological sexual arousal, and on relationships between arousal and proceptivity and receptivity. Goals of the project are three-fold: 1) To contribute to refinement of "APR" (attractivity-proceptivity-receptivity) theory regarding endocrine mediation of sociosexual behavior; 2) To relate psychophysical manifestations of sexual arousal to overt behavior and the concepts of proceptivity and receptivity; and 3) To begin a systematic approach to problems of sexual arousal dysfunction by using existing ranges of individual differences among rhesus females. Ultimate clinical benefits include identification and treatment of specific types of sexual dysfunction, and futher clarification of relationships between sexual arousal and dominance/aggression manifestations.