Molecular signals guiding dynamic cell movement during blood vessel growth

该项目旨在发现细胞如何在发育中的血管芽中相互作用。血管形成由动脉、毛细血管和静脉组成的复杂分支网络，为所有身体组织提供氧气和营养。血管的发育和维持依赖于血管壁中单个内皮细胞之间的运动和粘附的协调，但控制这些动作的信号是未知的。该项目旨在揭示血管树在发育过程中是如何形成的，这有望改善生物技术领域功能性血管化器官的工程。

This project aims to discover how cells interact within the developing blood vessel sprout. Blood vessels form complex branched networks composed of arteries, capillaries and veins that supply oxygen and nutrients to all body tissues. The development and maintenance of blood vessels depends on the coordination of movement and adhesion between individual endothelial cells in the vessel wall, but the signals controlling these actions are unknown. This project aims to reveal how the vascular tree forms during development, which is expected to improve the engineering of functional, vascularised organs in the biotech sector.