NONSHARED ENVIRONMENT GENES & ADOLESCENT MENTAL HEALTH

描述（改编自申请人摘要）：这是一项提案， 收集纵向随访（第二面板）数据的子样本， 有同性兄弟姐妹的家庭（719个原始家庭，450个随访家庭） 1988年至1990年研究的家庭。 最初的家庭由六个人组成 组，（1）MZ双胞胎，（2）DZ双胞胎，（3）有完整兄弟姐妹的继家庭， (4)有半个兄弟姐妹的继家庭，（5）有遗传基因的继家庭 （6）非离异家庭，有完整的兄弟姐妹。 一个主要 最初项目的目标是估算共同的环境影响 以及对环境措施的加性和非加性遗传影响。 选择家庭的特殊配置是为了最大限度地提高 设计的概念力量，而不是精确估计 对美国代表性样本的影响程度。样本， 然而，相对于其他发展中国家所使用方法， 问题研究 在随访研究中，研究者计划评估 环境，亲子互动（7项措施，包括录像 片段），兄弟姐妹互动，（5项措施，包括录像带 段），与非住宅母公司的关系（1个工具），同行 关系（1仪器），同伴关系（1仪器），其他 (Life事件清单，社会支持）。 还包括三个领域， 心理健康/疾病指标（5项指标，1项 人格发展优势（7项测量，1项 录像）和儿童青春期状态（1项测量）。 一些 家庭的特点，可能会缓和非共享的环境 影响也进行了评估;一般压力（1措施）和军事 冲突（4项措施，1个录像片段）。 此外，标准社交 并收集人口统计信息。 数据将由 由国家民意研究中心雇用和培训的采访者 （NORC）两次，每次间隔一周。 纵向的目的 这一部分是为了让调查人员能够解决一系列复杂的问题， 各种措施的变化动态问题 建议的（例如，遗传和环境的相对影响 随着时间的推移而变化？）

DESCRIPTION (Adapted from applicant's abstract): This is a proposal to collect longitudinal follow-up (second panel) data on a sub-sample of families with same-sex siblings (719 original families, 450 follow-up families) studied during 1988-1990. The original families consisted of six groups, (1) MZ twins, (2) DZ twins, (3) Step families with full siblings, (4) Step families with half siblings, (5) Step families with genetically unrelated children, (6) Non-divorced families with full siblings. A major goal of the initial project was to estimate shared environment influences and additive and non-additive genetic influences on environmental measures. The particular configuration of families was chosen to maximize the conceptual power of the design rather than precisely estimated the magnitude of effects on a representative sample of the U.S. The sample, however, is a very broad one relative to those used in other developmental studies. In the follow-up study the investigator plan to assess 7 domains of the environment, Parent-child interactions (7 measures, including a videotaped segment), sibling interaction, (5 measures, including a videotapes segment), relationships with non-residential parent(1 instrument), peer relationships (1 instrument), peer relationships (1 instrument), other (Life Event checklist, Social support). Also included are three domains of outcome measures; Mental health/Illness indicators (5 measures, 1 videotaped segment), Personality Developmental strengths (7 measures, 1 videotaped), and Child pubertal status (1 measure). A number of characteristics of the family that may moderate non-shared environmental effects are also assessed; General stressors (1 measure) and Martial conflict (4 measures, 1 videotaped segment). In addition, standard social and demographic information is gathered. The data will be collected by interviewers hired and trained by the National Opinion Research Center (NORC) on two occasion one week apart. The purpose of a longitudinal component is to allow the investigators to address a series of complex questions regarding the dynamics of change on the wide variety of measures proposed(e.g., does the relative influence of heredity and environment on change over time?)