INCIDENCE AND PATTERN OF BREAST MILK JAUNDICE

拟议的研究将调查该病的发生率和模式。 两组母乳喂养婴儿的母乳性黄疸。 此外，母乳性黄疸与 在母乳喂养的婴儿中，生理性黄疸将被夸大 检查一下。拟议的研究将试图回答以下问题 问题： 1.母乳性黄疸的发生率是否高于 目前文献中有报道吗？ 2.婴儿母乳性黄疸的发病率更高吗 有夸张的生理性黄疸吗？ 3.母乳的开始、高峰、严重程度和持续时间 黄疸与夸大性生理性黄疸的区别在于 新生儿？ 这项研究是关于黄疸的一系列研究中的第一项 母乳喂养的婴儿，并将提供哪些信息 从业者可以将他们的咨询和干预作为基础 这种综合症。第一组婴儿没有证据表明 高胆红素血症。第二组婴儿包括那些 出现了夸张的生理性黄疸。研究人群 将只包括正常的足月儿，没有并发症 产前和产中课程。两组的婴儿都将是 在出生后第2、3、5、7、9、11和13天使用 美能达/气盾公司生产的无创性胆红素101黄标仪 筛查设备。任何婴儿在第13天的屏幕上显示 超过10mgm/dl的水平将每隔一天跟踪一次，直到 黄标仪显示的水平低于10mgm/dl。 第I组和第II组婴儿中有 被确认为母乳黄疸的黄疸将被报告为 百分比。整体背离的一个样本检验 从文献中2%的报告率中观察到的百分比 将进行测试，以测试母乳的发生率 黄疸的发生率比文献中报道的要大。这个 第I组和第II组中已确认的母乳性黄疸发生率 将采用两样本检验进行比较的独立性 比例。每种类型黄疸的发病、高峰和消退 将以图形方式进行说明并使用适当的 汇总统计信息。将重复进行双向方差分析 将采取措施检查#年胆红素水平的趋势。 确诊为母乳性黄疸的人和那些 伴有夸大的生理性黄褐症。

The proposed study will investigate the incidence and pattern of breast-milk jaundice in two groups of breast-fed infants. Additionally, the relationship of breast-milk jaundice to exaggerated physiologic jaundice in breast-fed infants will be examine. The proposed study will attempt to answer the following questions: 1. Is the incidence of breast-milk jaundice greater than that currently reported in the literature? 2. Is the incidence of breast-milk jaundice greater in infants with exaggerated physiologic jaundice? 3. Does the onset, peak, severity, and duration of breast-milk jaundice differ from that of exaggerated physiologic jaundice in the newborn? This study represents the first in a series on jaundice in the breast-fed infant and will provide information from which practioners can base their counseling and interventions regarding this syndrome. Infants in Group I have no evidence of hyperbilirubinemia. Infants in Group II include those infants who developed exaggerated physiologic jaundice. The study population will include only normal full term infants with uncomplicated prenatal and intrapartum courses. Infants in both groups will be screened on days 2,3,5,7,9,11, and 13 following birth using the Minolta/Air Shields Jaundice Meter 101, a non-invasive bilirubin screening device. Any infant whose screen on day 13 indicates a level greater than 10 mgm/dl will be followed every other day until the jaundice meter indicates a level below 10 mgm/dl. The total number of infants in Group I and in Group II who have jaundice identified as breast-milk jaundice will be reported as a percentages. A one-sample test of the departure of the overall observed percentage from the 2% reported rate in the literature will be performed to test whether the incidence of breast-milk jaundice is greater than the rate reported in the literature. The incidence of identified breast-milk jaundice in Groups I and II will be compared using the two-sample test of independent proportions. The onset, peak, and decline of each type of jaundice will be graphically illustrated and described using appropriate summary statistics. Two-way analysis of variance will repeated measures will be applied to examine trends in bilirubin levels over time between those with identified breast-milk jaundice and those with exaggerated physiologic jaundice.