MASSAGING HIV-1-EXPOSED INFANTS

按摩机构体重增加、国家组织、社会责任 早产儿的认知表现和减少应激行为 婴儿。触摸也与大脑的变化呈正相关 结构和改善免疫功能。不能茁壮成长，免疫力差 功能、发育和认知缺陷是严重的 对感染艾滋病毒的婴儿来说，这是一个问题。这些数据表明，使用按摩时 感染艾滋病毒的婴儿将促进体重增加，促进发育 性能和增强免疫功能。八名感染艾滋病毒的早产儿 新生儿将被随机分配到治疗(按摩)和对照组 转移到中间护理病房时的情况 在医学上都是稳定的。我们之前使用的按摩程序 这项研究将使用三个15分钟的按摩期 每日一次，为期10天。睡眠/醒来行为(包括压力 面部表情、握紧拳头和打哈欠等行为将被 记录和心率将在第一天和最后几天进行监测 评估睡眠/清醒组织、活动和压力水平的研究时间。 在那几天将采集尿样和血样以检测皮质醇， 生长激素和儿茶酚胺水平。发展绩效将是 使用BRACELTON新生儿行为评估量表-堪萨斯州 补充剂。父母/婴儿二人组将在UM特别节目中跟进 3个月和6个月校正年龄的免疫学诊所。睡眠/唤醒行为， 应激行为和免疫功能将在每个诊所进行评估。 参观。贝利婴儿发展量表也将在6岁时进行 几个月的修正年龄。预计接触艾滋病毒的早产儿 被按摩的人会增加更多的体重，表现出优越的发育 表现，表现出较少的压力行为，并提高了免疫力 功能正常。

Massage facilities weight gain, state organization, social responsitivity and cognitive performance and reduces stress behaviors in preterm newborn infants. Touch has also been positively associated with changes in brain structure and improved immune functioning. Failure-to-thrive, poor immune functioning, and developmental and cognitive deficits are significant problems for the HIV-exposed infant. These data suggest using massage with HIV-exposed infants will facilitate weight gain, improve developmental performance and enhance immune functioning. Eight HIV-exposed preterm newborns will be randomly assigned to treatment (massage) and control conditions at the time they are transferred to the intermediate care units and are medically stable. The massage procedure used in our previous studies will be used in this study: three 15-minute periods of massage daily for a 10 day period. Sleep/wake behaviors (including stress behaviors such as facial grimaces, clenched fists and yawning) will be recorded and heart rate will be monitored on the first and last days of the study period to assess sleep/wake organization, activity and stress levels. Urine and blood samples will be collected on those days to assay cortisol, growth hormone and catecholamine levels. Developmental performance will be assessed using the Brazelton Neonatal Behavior Assessment Scale-Kansas Supplements. The parent/infant dyad will be followed in the UM Special Immunology Clinic at 3 and 6 months corrected age. Sleep/wake behavior, stress behavior and immune functioning will be assessed at each clinic visit. Bayley Scales of Infant Development also will be administered at 6 months corrected age. It is expected that the HIV--exposed preterm infants who are massaged will gain more weight, show superior developmental performance, exhibit fewer stress behaviors and have improved immune functioning.