COMPONENTS OF AUDITORY COMPREHENSION IN APHASIC PATIENTS

本项目的主要目标是为建模做出贡献 听觉理解所涉及的过程，通过一个 更好地理解听觉理解的缺陷 与“无语法”失语症有关。建议 操纵是为了更准确地定义受损害的人 听觉理解的组成部分，以研究分离 和联想在理解能力上，并决定 是否有任何现在表现出的解离在生产性 “无语法”失语症的能力反映在 理解。具体地说，困难的可能性 “纯定义否定”中否定语素的处理 可能与处理其他语义的困难有关 将对现象进行调查，以确定是否存在 理论上有趣的语义定义函数集 有失语症风险的人。此外，如果这些问题是 与语义访问过程中的更改相关，可能是 可以观察到它们与 在词汇判断任务中没有表现出正常的启动。这 该项目还开始检查一个人的听觉理解 与所谓的“无语法”相关的各种句子类型 失语症患者范围广泛，以确定1)是否 相同的功能障碍一致地影响所有牵连的判决 类型和2)难度是否特定于某一特定 失语症亚组。最后，本项目启动了对 听理解能力的恢复超过了通常的时期 与自然恢复有关。观察到以下方面的改善 中风后两年以上的患者建议更多 系统地观察进展情况将是有用的。在追求 这些目标，一系列的临床和实验测试将是 开发的目的是允许对患者进行充分的描述和观察 进展和选择患者进行适当的实验 学习。拟议的工作将包括小组研究和案例研究 由考虑中的假设所规定的研究和 可用的患者档案。

The primary goal of this project is to contribute to the modeling of the processes involved in auditory comprehension, through a better understanding of the deficit in auditory comprehension that has been associated with "agrammatic" aphasia. Proposed manipulations are intended to more sharply define the impaired components of auditory comprehension, to investigate dissociations and associations in comprehension abilities and to determine whether any of the dissociations now demonstrated in the productive abilities of "agrammatic" aphasics are mirrored in components of comprehension. Specifically, the possibility that difficulty processing the negative morpheme in "pure definitional negatives" may be associated with difficulty processing other semantic phenomena will be investigated to determine if there are theoretically interesting sets of semantically defined functions that are at risk in aphasia. Furthermore, if these problems are related to a change in semantic access procedures, it may be possible to observe consistent relations between them and the failure to show normal priming in lexical decision tasks. This project also begins to examine the auditory comprehension of a variety of sentence types associated with so-called "agrammatic" aphasia across a broad spectrum of patients to determine 1) whether the same dysfunction uniformly effects all implicated sentence types and 2) whether the difficulty is specific to any particular aphasic sub-group. Finally, this project initiates a study of the recovery of auditory comprehension beyond the period usually associated with spontaneous recovery. Observed improvements in patients at a point more than two years post-stroke suggest more systematic observation of progress would be useful. In pursuing these goals, a battery of clinical and experimental tests will be developed to allow adequate description of patients both to observe progress and to select patients for appropriate experimental studies. Proposed work will include both group studies and case studies as dictated by the hypotheses under consideration and the profiles of the patients available.