COMPONENTS OF AUDITORY COMPREHENSION IN APHASIC PATIENTS

这个项目的主要目标是有助于建模 听觉理解的过程，通过一个 更好地理解听觉理解的缺陷， 与失语症有关 提出 操作旨在更清晰地定义受损的 听觉理解的组成部分，调查解离 和联想的能力，并确定 是否有任何的分离，现在表明，在生产 “语法”失语症患者的能力反映在 理解力 具体来说，困难的可能性 “纯定义否定词”中否定语素的加工 可能与处理其他语义的困难有关 将对这些现象进行调查，以确定是否存在 语义定义函数的理论上有趣的集合 失语症的危险因素。 此外，如果这些问题 与语义访问程序的变化有关， 可以观察到它们之间的一致关系， 在词汇判断任务中没有表现出正常的启动。 这 项目还开始检查一个人的听觉理解能力， 与所谓的“语法”相关的各种句子类型 广泛的失语症患者，以确定1）是否 同样功能障碍同样影响所有牵连判决 （2）是否有特殊的困难， 失语亚组。 最后，本项目启动了对 听觉理解力的恢复通常超过 与自然恢复有关。 观察到的改善 中风后两年以上的患者 对进展情况进行系统的观察将是有益的。 追求 为了实现这些目标，将进行一系列临床和实验测试， 开发以允许充分描述患者， 并选择患者进行适当的实验 问题研究 拟议的工作将包括小组研究和个案研究 研究所规定的假设正在考虑和 病人的资料。

The primary goal of this project is to contribute to the modeling of the processes involved in auditory comprehension, through a better understanding of the deficit in auditory comprehension that has been associated with "agrammatic" aphasia. Proposed manipulations are intended to more sharply define the impaired components of auditory comprehension, to investigate dissociations and associations in comprehension abilities and to determine whether any of the dissociations now demonstrated in the productive abilities of "agrammatic" aphasics are mirrored in components of comprehension. Specifically, the possibility that difficulty processing the negative morpheme in "pure definitional negatives" may be associated with difficulty processing other semantic phenomena will be investigated to determine if there are theoretically interesting sets of semantically defined functions that are at risk in aphasia. Furthermore, if these problems are related to a change in semantic access procedures, it may be possible to observe consistent relations between them and the failure to show normal priming in lexical decision tasks. This project also begins to examine the auditory comprehension of a variety of sentence types associated with so-called "agrammatic" aphasia across a broad spectrum of patients to determine 1) whether the same dysfunction uniformly effects all implicated sentence types and 2) whether the difficulty is specific to any particular aphasic sub-group. Finally, this project initiates a study of the recovery of auditory comprehension beyond the period usually associated with spontaneous recovery. Observed improvements in patients at a point more than two years post-stroke suggest more systematic observation of progress would be useful. In pursuing these goals, a battery of clinical and experimental tests will be developed to allow adequate description of patients both to observe progress and to select patients for appropriate experimental studies. Proposed work will include both group studies and case studies as dictated by the hypotheses under consideration and the profiles of the patients available.