A NEW FINGER JOINT PROSTHESIS

一种新的手指关节假体将被设计和测试。会的 使用钛铰链。铰链区域将被封装在 其外部将具有完整纹理表面的弹性夹克 旨在促进软组织向内生长和依附。这可能会 减少关节屈曲部位周围反应性瘢痕组织的形成 植入物，改善关节功能。锥形近端和 假体的远端将使用一种多孔的烧结金属。 表面允许在不使用粘合剂的情况下植入装置 当被插入骨髓腔时，骨水泥。骨生长 进入多孔金属表面的是固定的手段。一个完全漏洞百出的 表面设备还提供了减少细菌潜在性的优势 种植部位的定植，通常是一种灾难性的并发症 矫形假体。一系列12个原型将在Flex中进行测试 体外循环1000万次，以表征设备的可靠性。跟随 也就是说，6个假体将被植入成年的新西兰人的膝关节 新西兰大白兔，用硅橡胶关节垫片假体 对侧植入作为对照。8周后，这些动物将 牺牲，并移除假体和周围组织 光镜和扫描电子显微镜下的组织病理学评价。一个 器械固定与组织包膜结构的定量比较 将会成为可能。

A new finger joint prosthesis is to be designed and tested. It will utilize a titanium hinge. The hinge area is to be encapsulated in an elastomeric jacket whose exterior will have an integrally textured surface designed to promote soft tissue ingrowth and attachment. This potentially minimizes reactive scar tissue formation around the flexing part of the implant, resulting in improved joint function. The tapered proximal and distal terminations of the prosthesis will utilize a porous, sintered metal surface to permit implantation of the device without the use of adhesive cements when inserted into the medullary cavity of the bone. Bone growth into the porous metal surface is the means of fixation. A totally porous surface device offers the advantage also of reduced potential for bacterial colonization of the implant site, a generally disastrous complication with orthopedic prostheses. A series of 12 prototypes will be flex tested in vitro for 10 million cycles to characterize device reliability. Following that, 6 prostheses will then be implanted in the knee joint of adult New Zealand white rabbits, with silicone rubber joint spacer prostheses contralaterally implanted as controls. After 8 weeks, the animals will be sacrificed, and the prostheses and surrounding tissues removed for histopathologic evaluation using light and scanning electron microscopy. A quantitative comparison of device fixation and tissue capsule structure will then be possible.