CRYOPROBES FOR ULTRASONICALLY GUIDED CANCER TREATMENT

我们计划开发一系列产品来进行经皮 冷冻外科治疗前列腺癌、肝癌、脑癌和胰腺癌。因为 与目前相关的发病率、死亡率和高昂的成本 经皮前列腺癌的可用治疗方式 经直肠超声引导下的冷冻外科手术可能会提供 更少的病态治疗，应该被证明是一种更可取的模式 治疗。这项研究的具体目的如下： 一、确定超声波的理想性能特性 探头和其他设备需要执行安全、简单的 冷冻手术程序 二、开发医用合适的仪器(冷冻探头)，用于 使用新开发的技术进行冷冻外科手术。 三、评估经皮前列腺电切术的安全性和有效性 使用研制的仪器在超声引导下进行冷冻手术。

We propose to develop a series of products to perform percutaneous cryosurgery on cancers of the prostate, liver, brain and pancreas. Because of the morbidity, mortality and high costs associated with currently available treatment modalities for prostatic cancers, percutaneous cryosurgery under transrectal ultrasound guidance could potentially provide much less morbid treatment and should prove to be a more desirable mode of treatment. The specific aims of this study is the following: I. to determine the ideal performance characteristics for ultrasound probes and the other equipment needed to perform a safe, simple cryosurgical procedure II. to develop medical suitable instruments (cryoprobes) with which to perform cryosurgery using newly developed technology. III. to assess the safety and efficacy of percutaneous prostate cryosurgery under ultrasound guidance using the developed instruments.