AMPLIFIERS--DENSE ELECTRODE ARRAY ELECTROENCEPHALOGRAPHY

这项研究将开发一种廉价的电子- 脑电图（EEG）放大器系统，适用于密集（128或256） 电极阵列这些阵列将提供必要的测量 对于受MRI数据约束的新的源定位算法， 大脑皮层的电活动贯穿大脑的三个维度， 颅内间隙 虽然这些图像的解剖分辨率 仍然有待确定，它们是为每个毫秒样本生成的 电子记录，因此，提供信息与时间 代谢和血流动力学方法无法解决 神经成像这种时间分辨率可能是必要的研究 皮层网络的认知活动。 主要进展 这项新技术所承诺的可视化动态大脑功能将 在心理学，神经学，精神病学， 教育和人为因素研究。 在五年内，这项研究 这将为广泛的临床应用提供基础。 从注意力缺陷到公共卫生问题 阿尔茨海默氏痴呆症

The proposed research would develop an inexpensive electro- encephalographic (EEG) amplifier system suitable for dense (128 or 256) electrode arrays. These arrays would provide the measurements necessary for new source localization algorithms constrained by MRI data that image the electrical activity of the cortex throughout the three dimensions of intracranial space. Although the anatomical resolution of these images remains to be determined, they are generated for each millisecond sample of electrical recording, and thus, provide information with a temporal resolution not possible with metabolic and hemodynamic methods of neuroimaging. This temporal resolution may be necessary to research the cognitive activity of cortical networks. The major advances in visualizing dynamic brain function promised by this new technology will have immediate applications in psychology, neurology, psychiatry, education, and human factors research. Within 5 years, this research will provide the basis for widespread clinical applications of this technology to public health problems ranging from attention deficit disorder to Alzheimer's dementia.