INTRAVENTRICULAR AXIAL FLOW PUMP ARTIFICIAL HEART

一种独特的旋转人工心脏，用于永久植入 有可能克服感染、血栓栓塞症和 设备的复杂性使现有患者能够长期获得支持 气动和电动人工心脏不切实际。新系统 取决于微型电机、轴流泵的成功，以及 热解碳轴承系统，共同允许一个移动部件 不需要在内部植入阀门或轴封的装置 左心室腔内，并提供超过 101次/分钟。 这是一份重新提交的建议书，修改后包括制造和 测试电机、泵和轴承系统，而不是强调 只是按照先前的计划安装了泵。关键的热解碳轴承 零部件已成功制造，马达性能可靠 设计计算预测卓越的性能，专家CAD/CAM 协助设计和制造泵叶片的合作已 已经安排好了。因此，研究计划将提供具有特征的数据 系统的压力、流量和效率特性，以及 量化由轴承和轴承单独引起的溶血 泵叶片。这将足以确定基本的可行性 这种方法的重要性。在第二阶段，设计将进行优化和动物 将进行测试，以证明没有血栓形成。

A unique rotary artificial heart for permanent implantation has the potential to overcome the problems of infection, thromboembolism, and device complexity which make long term support of patients with existing pneumatic and electric artificial hearts impractical. The new system depends on the success of the miniature motor, axial flow pump, and pyrolytic carbon bearing system which together permit a one-moving-part device requiring no valves or shaft seal to be implanted within the cavity of the left ventricle and to provide a cardiac output in excess of 10 1/min. This is a resubmitted proposal modified to include fabrication and testing of the motor, pump, and bearing system rather than emphasizing only the pump as previously planned. The key pyrolytic carbon bearing components have already been successfully fabricated, reliable motor design calculations predict excellent performance, and expert CAD/CAM collaboration to assist in design and fabrication of the pump blading has been arranged. Thus, the research plan will provide data characterizing the pressure, flow, and efficiency characteristics of the system, and quantifying the hemolysis caused independently by both the bearings and pump blading. This will be sufficient to determine the basic feasibility of the approach. During Phase II, the design will be optimized and animal tests will be conducted to demonstrate freedom from thrombosis.