COMPUTER-ASSISTED SMOKING CESSATION FOR HEAVY SMOKERS

流行病学调查的最新数据，实验研究的回顾， 以及健康创新公司进行的研究表明， 戒烟计划对重度吸烟者的成功率低于 他们的吸烟量较轻。 不幸的是，正如Shiffman所指出的， 目前还没有行为治疗方法 根据尼古丁依赖程度的建议。 是的， 因此，需要治疗方案，以满足特殊需要， 烟瘾很大。 LifeSign计算机辅助吸烟治疗计划提供了一个 一个结构化的，逐步退出计划，已被证明是na有效的 和商业上可行的戒烟计划。 一种规格的 计算机辅助程序的另一个优点是，它们允许精确量化 治疗参数，因此易于修改， 实验测试其影响。 本提案描述了对LifeSign计划的修改， 可能会改善重度吸烟者的预后。 修改 该计划包括撤回曲线的长度和速度的变化， 用户界面，以进一步改变撤回的速度。 小规模 比较修改后的程序与原始LifeSign的结局试验 该计划将使我们能够评估修改的影响， 为第二阶段资金征集做准备的最终计划变更 进行大规模的疗效试验

Recent data from epidemiological surveys, reviews of experimental studies, as well as research conducted by Health Innovations, suggest that self-help smoking cessation programs are less successful for heavy smokers than for their lighter smoking counterparts. Unfortunately, as Shiffman noted, there are currently no behavioral treatments that provide differential recommendations on the basis of degree of nicotine dependence. There is, therefore, a need for treatment programs that meet the special needs of heavy smokers. The LifeSign computer assisted smoking treatment program provides a structured, gradual withdrawal program that has proven to be na effective and commercially viable smoking cessation program. One strength of computer assisted programs is that they allow for precise quantification of treatment parameters and are thus readily amenable to modification and experimental testing of their impact. The present proposal describes modifications to the LifeSign program that are likely to improve outcome rates with heavy smokers. Modifications of the program include changes in length and rate of the withdrawal curve and a user interface to further alter the pace of withdrawal. A small-scale outcome trial comparing the modified program with the original LifeSign program will allow us to assess the impact of the modifications and to make final program changes in preparation for solicitation of Phase II funding for a large-scale efficacy trial.