SOUTHEASTERN OKLAHOMA BIOMEDICAL SCIENCES PROGRAM

SEOSU少数民族生物医学科学的总体目标 该计划旨在加强生物医学研究能力， 机构，并进一步加强其能力，提供介绍 生物医学研究经验，以少数民族学生（特别是 美国印第安人）由该机构提供服务。 资助的研究项目 该计划将影响生物分析学科 化学、生物无机化学和物理生物化学，以及 有助于在SEOSU化学程序的丰富。 学生 参与化学课程和本科研究经验 将更好地准备追求科学研究生教育。 本申请提出了三个研究项目。 整体 每个项目的目标列在项目标题之后。 1："涉及含硫配体的金属簇合物" 金属簇合剂的合成和多核的表征 金属物种）。 2. "生物分析化学中的聚合物吸附剂"（开发新的 致癌多环芳烃的分离方法 使用聚合物吸附剂的顺序模式色谱法）。 3. "用于生物医学应用的铜离子标记抗体" （开发用于光学和电子显微镜的免疫组织化学试剂， 并且适合于放射性同位素载体。

The broad overall objectives of the SEOSU Minority Biomedical Sciences Program are to strengthen the biomedical research capabilities of the institution, and further enhance its abilities to provide introductory biomedical research experiences to the minority students (particularly American Indians) served by the institution. The research projects funded by this program will impact upon the disciplines of bioanalytical chemistry, bioinorganic chemistry, and physical biochemistry, and contribute to the enrichment of the chemistry program at SEOSU. Students involved in the chemistry program and undergraduate research experiences will be better prepared to pursue graduate education in the sciences. Three research projects are proposed in this application. The overall objective of each project is listed immediately following the project title. 1: "Metal Cluster Compounds Involving Sulfur-Containing Ligands" (Synthesis of metal-clustering agents and characterization of polynuclear metal species.) 2. "Polymeric Adsorbents in Bioanalytical Chemistry" (Developing new separation methods for carcinogenic polycyclic aromatic hydrocarbons using sequential-mode chromatography with polymeric adsorbents.) 3. "Copper CLuster-labeled Antibodies for Biomedical Applications" (Developing immunohistochemical reagents for light and electron microscopy, and suitable for radioisotope carriers.)