Cognitive dysfunction in SLE: diagnostic tools, biological correlates and patient impact

狼疮(SLE)是一种慢性自身免疫性疾病，影响身体的许多部位，包括大脑。狼疮脑雾，即思维、注意力和记忆力障碍，是很常见的，但人们对它发生的原因以及可以采取的措施知之甚少。这项研究旨在改进测量狼疮脑雾的工具，并检查任何预测因素，包括新的生物标志物或可以识别风险患者的成像结果。还将衡量对患者功能和福祉的影响。

Lupus (SLE) is a chronic autoimmune disease affecting many parts of the body including the brain. Lupus brain fog, or trouble with thinking, concentration and memory, is common, but little is known about why it occurs and what can be done about it. This study aims to improve tools to measure Lupus brain fog, and examine for any predictors, including new biological markers or imaging findings that can identify patients at risk. Effects on patient’s function and well-being will also be measured.